Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105323 | 0.88 | TDP1 (0.42) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL27855225 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL2729293 | 0.83 | TDP1 (0.43) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL8520350 | 0.82 | ENPP2 (0.42) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL23653864 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL22134173 | 0.79 | MMP8 (0.39) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL14457019 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL8995845 | 0.75 | CYP2C19 (0.51) | MAPTKDM4ESMN1; SMN2CYP2C19TSHR | |
| SCHEMBL7438151 | 0.71 | MAPT (0.50) | ALDH1A1HSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL1678150 | 0.71 | SMN1; SMN2 (0.66) | ALDH1A1HSD17B10ALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-11-06 | — | — | US | disclosed |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-01-14 | — | — | US | disclosed |
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2024-03-14 | — | — | US | disclosed |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | ALDH1A1 1880/4885HSD17B10 235/4885ALOX15 3920/4885 |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | MAPT, FABP7, HTT | ALDH1A1 1880/4885HSD17B10 235/4885ALOX15 3920/4885 |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | MAPT, FABP7, HTT | ALDH1A1 1691/4885HSD17B10 218/4885ALOX15 3855/4885 |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | MAPT, FABP7, HTT | ALDH1A1 2088/4885HSD17B10 246/4885ALOX15 3895/4885 |
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | ALDH1A1 1923/4885HSD17B10 203/4885ALOX15 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.