SCHEMBL294107

SCHEMBL294107

CC(C)OC(=O)C1CC1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CHRNB2 P17787 6/20 0.34
CHRNA3 P32297 6/20 0.34
CHRNA4 P43681 6/20 0.34
CHRNB4 P30926 4/20 0.34
CHRNA7 P36544 4/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CHRNB3 Q05901 2/20 0.32
CHRNA6 Q15825 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1297587 0.87 TSHR (0.46) TSHRPOLBNPSR1ALDH1A1KDM4E
SCHEMBL10121177 0.87 TSHR (0.46) TSHRPOLBNPSR1ALDH1A1KDM4E
SCHEMBL1244593 0.86 POLB (0.41) TSHRPOLBNPSR1ALDH1A1KDM4E
SCHEMBL1246335 0.86 TSHR (0.33) TSHRPOLBNPSR1ALDH1A1KDM4E
SCHEMBL1246381 0.84 SLC6A2 (0.33) TSHRPOLBNPSR1CHRNB2CHRNA3
SCHEMBL21097351 0.82 MAPT (0.37) POLBNPSR1ALDH1A1MAPTCHRNB2
SCHEMBL21097352 0.82 MAPT (0.37) POLBNPSR1ALDH1A1MAPTCHRNB2
SCHEMBL1245764 0.81 SLC6A4 (0.37) ALDH1A1MAPTCHRNB2CHRNA3CHRNA4
SCHEMBL18913008 0.81 TSHR (0.34) TSHRPOLBNPSR1ALDH1A1LMNA
SCHEMBL27791146 0.81 PPP5C (0.33) TSHRPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030089885-A1 Use of low molecular weight acetal, alcohol, acylated alcohol and ester compounds to block or reduce odor of carboxylic acids SENOMYX, INC. 2003-05-15 US claimed
WO-2002085294-A2 USE OF LOW MOLECULAR WEIGHT ACETAL, ALCOHOL, ACYLATED ALCOHOL AND ESTER COMPOUNDS TO BLOCK OR REDUCE ODOR OF CARBOXYLIC ACIDS SENOMYX, INC. (US) 2002-10-31 WO claimed
EP-1683783-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
EP-1683782-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
EP-1120402-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2008-06-25 EP disclosed
CN-1310924-C Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2007-04-18 CN disclosed
EP-1683782-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
EP-1683783-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
CN-1246299-C Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2006-03-22 CN disclosed
US-7009079-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
CN-1616465-A Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2005-05-18 CN disclosed
US-6670500-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-30 US disclosed
US-20030089885-A1 Use of low molecular weight acetal, alcohol, acylated alcohol and ester compounds to block or reduce odor of carboxylic acids SENOMYX, INC. 2003-05-15 US disclosed
WO-2002085294-A2 USE OF LOW MOLECULAR WEIGHT ACETAL, ALCOHOL, ACYLATED ALCOHOL AND ESTER COMPOUNDS TO BLOCK OR REDUCE ODOR OF CARBOXYLIC ACIDS SENOMYX, INC. (US) 2002-10-31 WO disclosed
US-6469198-B2 OBTAINED BY CONTACTING N-SALICYLIDENEAMINOALCOHOL WITH MONO OR DIVALENT COPPER COMPOUND; FORMATION OF OPTICALLY ACTIVE CYCLOPROPANE-CARBOXYLIC ESTER FROM PROCHIRAL OLEFIN AND DIAZOACETIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-22 US disclosed
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-10 US disclosed
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-01 US disclosed
CN-1313277-A Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2001-09-19 CN disclosed
EP-1120402-A2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed
EP-1120401-A2 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same AP1M1, UBA3, AP1S1 TSHR 4320/4885POLB 544/4885NPSR1 3706/4885
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SOD1, XDH, NFXL1 TSHR 2499/4885POLB 1324/4885NPSR1 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.