Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412628 | 1.00 | RAB9A (0.49) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL30446287 | 0.77 | KCNMA1 (0.60) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL12720802 | 0.73 | AGTR1 (0.71) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL12720811 | 0.71 | AGTR1 (0.58) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL27177866 | 0.67 | OPRK1 (0.77) | RAB9AAGTR1NPC1OPRK1KMT2A | |
| SCHEMBL27177860 | 0.67 | OPRK1 (0.77) | RAB9AAGTR1NPC1OPRK1KMT2A | |
| SCHEMBL12720825 | 0.67 | AGTR1 (0.66) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL1028452 | 0.67 | AGTR1 (0.91) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL12955841 | 0.66 | AGTR1 (0.60) | RAB9AAGTR1NPC1NCOA3NCOA1 | |
| SCHEMBL1028098 | 0.66 | AGTR1 (0.74) | RAB9AAGTR1NPC1NCOA3NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204401-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022040747-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2022-03-03 | — | — | WO | disclosed |