Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720811 | 0.82 | AGTR1 (0.58) | NPC1RAB9AAGTR1NCOA1NCOA3 | |
| SCHEMBL12720802 | 0.81 | AGTR1 (0.71) | NPC1RAB9AAGTR1NCOA1NCOA3 | |
| SCHEMBL29412628 | 0.77 | RAB9A (0.49) | NPC1RAB9AAGTR1NCOA1NCOA3 | |
| SCHEMBL29412636 | 0.77 | RAB9A (0.49) | NPC1RAB9AAGTR1NCOA1NCOA3 | |
| SCHEMBL27177866 | 0.77 | OPRK1 (0.77) | NPC1RAB9AAGTR1OPRK1KMT2A | |
| SCHEMBL27177860 | 0.77 | OPRK1 (0.77) | NPC1RAB9AAGTR1OPRK1KMT2A | |
| SCHEMBL12720819 | 0.75 | AGTR1 (0.71) | NPC1RAB9AAGTR1NCOA1NCOA3 | |
| SCHEMBL14886092 | 0.75 | KCNMA1 (1.00) | KCNMA1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27178078 | 0.74 | OPRK1 (0.77) | NPC1RAB9AAGTR1OPRK1KMT2A | |
| SCHEMBL27178063 | 0.74 | OPRK1 (0.77) | NPC1RAB9AAGTR1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323558-A | Compounds and methods for treating diseases | 艾特里提治疗有限公司 | 2023-06-23 | — | — | CN | disclosed |