Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL3254715 | 0.93 | REN (0.31) | REN | |
| Phenylalanine SCHEMBL294178 | 0.86 | REN (0.36) | RENANPEPRNPEPDNPEP | |
| Histidine SCHEMBL7763228 | 0.82 | — | — | |
| Histidine SCHEMBL5577985 | 0.82 | — | — | |
| Histidine SCHEMBL5577952 | 0.80 | — | — | |
| Dl-Phenylalanine SCHEMBL29201498 | 0.80 | ALPI (0.41) | REN | |
| Phenylalanine SCHEMBL10379633 | 0.79 | ANPEP (0.40) | RENANPEPRNPEPDNPEP | |
| Proline SCHEMBL1543509 | 0.78 | — | — | |
| Histidine SCHEMBL5578200 | 0.78 | — | — | |
| Proline SCHEMBL10428636 | 0.78 | ANPEP (0.38) | RENANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445325-B1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2010-05-26 | — | — | EP | claimed |
| EP-2463378-B1 | Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof | HAYASHIBARA CO (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-2463378-A1 | Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-1229112-B1 | ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-1284286-B1 | ALPHA-ISOMALTOSYLTRANSFERASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7811797-B2 | α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-10-12 | — | — | US | disclosed |
| EP-1445325-B1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-7718404-B2 | α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-05-18 | — | — | US | disclosed |
| US-7592160-B2 | Processes for producing isomaltose and isomaltitol and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080032350-A1 | Alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-02-07 | — | — | US | disclosed |
| US-20080003651-A1 | alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-01-03 | — | — | US | disclosed |
| US-7241606-B2 | α-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-07-10 | — | — | US | disclosed |
| US-7192746-B2 | α-Isomaltosyltransferase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20060240531-A1 | Processes for producing isomaltose and isomaltitol and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-10-26 | — | — | US | disclosed |
| US-20050009017-A1 | Alpha-isomaltosyltransferase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1445325-A1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-20030194762-A1 | Alpha-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1284286-A1 | ALPHA-ISOMALTOSYLTRANSFERASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-1229112-A1 | ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009017-A1 | Alpha-isomaltosyltransferase, process for producing the same and use thereof | UGGT1, B4GALT1, GALE | REN 3771/4885ANPEP 765/4885RNPEP 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.