Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472520 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 | |
| SCHEMBL28229506 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 | |
| SCHEMBL40676 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 | |
| SCHEMBL472408 | 0.81 | KIF11 (0.56) | ALDH1A1KIF11HSD17B10KDM4EPTGS2 | |
| SCHEMBL28117888 | 0.81 | KIF11 (0.38) | ALDH1A1KIF11ALDH1A3ALDH3A1NPFFR1 | |
| SCHEMBL5188027 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 | |
| SCHEMBL6849159 | 0.79 | KIF11 (0.55) | ALDH1A1KIF11HSD17B10KDM4EPTGS2 | |
| SCHEMBL28502765 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 | |
| SCHEMBL17345173 | 0.78 | KIF11 (0.53) | ALDH1A1KIF11HSD17B10KDM4EPTGS2 | |
| SCHEMBL6853514 | 0.78 | KIF11 (0.53) | ALDH1A1KIF11ALDH1A3VCAM1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680608-A1 | 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS | MMV Medicines for Malaria Venture (CH) | 2026-01-21 | — | — | EP | disclosed |
| WO-2022108980-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-27 | — | — | WO | disclosed |
| CN-109496213-B | Spiro compounds and methods of making and using the same | H.隆德贝克有限公司 | 2022-03-04 | — | — | CN | disclosed |