5-Oh-Dpat

5-Oh-Dpat

SCHEMBL29420186

CCCN(CCC)C1CCc2c(O)cccc2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 10/20 1.00
DRD3 P35462 8/20 1.00
DRD4 P21917 3/20 1.00
DRD1 P21728 3/20 1.00
HTR1A P08908 1/20 1.00
DRD5 P21918 1/20 1.00
HTR7 P34969 1/20 1.00
ADRB2 P07550 1/20 1.00
CYP1A2 P05177 1/20 0.81
CYP3A4 P08684 1/20 0.81
CYP2D6 P10635 1/20 0.81
TSHR P16473 1/20 0.81
NFKB1 P19838 1/20 0.81
THPO P40225 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Oh-Dpat SCHEMBL5705486 1.00 DRD2 (1.00) DRD2DRD3DRD4DRD1HTR1A
5-Oh-Dpat SCHEMBL17446178 1.00 DRD2 (1.00) DRD2DRD3DRD4DRD1HTR1A
5-Oh-Dpat SCHEMBL30201073 1.00 DRD2 (1.00) DRD2DRD3DRD4DRD1HTR1A
5-Oh-Dpat SCHEMBL279021 1.00 DRD2 (1.00) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL21262950 0.94 DRD2 (0.90) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL21083262 0.94 DRD2 (0.90) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL29062563 0.94 DRD2 (0.88) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL24314254 0.92 DRD2 (0.91) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL11198430 0.91 DRD2 (0.84) DRD2DRD3DRD4DRD1HTR1A
SCHEMBL11199129 0.91 DRD2 (0.84) DRD2DRD3DRD4DRD1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12485181-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-12-02 US claimed
US-12383625-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-08-12 US claimed
US-12383626-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-08-12 US claimed
US-20240316208-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS (AL), INC. (US) 2024-09-26 US claimed
US-20240293560-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS (AL), INC. (US) 2024-09-05 US claimed
US-11944618-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents SERINA THERAPEUTICS, INC. (US) 2024-04-02 US claimed
US-20230009076-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS, INC. (US) 2023-01-12 US claimed
EP-3990026-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES Serina Therapeutics, Inc. (US) 2022-05-04 EP claimed
US-11298350-B2 Subcutaneous delivery of polymer conjugates of therapeutics agents SERINA THERAPEUTICS, INC. (US) 2022-04-12 US claimed
CN-114258309-A Polyoxazoline-drug conjugates with novel pharmacokinetic properties 塞瑞纳治疗公司 2022-03-29 CN claimed
US-20260131012-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES SERINA THERAPEUTICS (AL), INC. (US) 2026-05-14 US disclosed
US-12485181-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-12-02 US disclosed
US-12428408-B2 Fused heterocyclic mescaline derivatives Enveric Biosciences Canada Inc. (CA) 2025-09-30 US disclosed
US-12383626-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-08-12 US disclosed
US-12383625-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties SERINA THERAPEUTICS (AL), INC. (US) 2025-08-12 US disclosed
US-20220354841-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2022-11-10 US disclosed
EP-3990026-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES Serina Therapeutics, Inc. (US) 2022-05-04 EP disclosed
US-11298350-B2 Subcutaneous delivery of polymer conjugates of therapeutics agents SERINA THERAPEUTICS, INC. (US) 2022-04-12 US disclosed
CN-114258309-A Polyoxazoline-drug conjugates with novel pharmacokinetic properties 塞瑞纳治疗公司 2022-03-29 CN disclosed
US-11285147-B2 Neuroprotective agents for treatment of neurodegenerative diseases WAYNE STATE UNIVERSITY (US) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12383625-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties CYP3A5, SPOP, CYP2C19 DRD2 662/4885DRD3 695/4885DRD4 598/4885
US-20230009076-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES CYP3A5, CYP2C19, CYP3A7 DRD2 520/4885DRD3 644/4885DRD4 420/4885
US-11944618-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents CD44, CD47, LNPEP DRD2 4535/4885DRD3 4646/4885DRD4 4501/4885
US-12428408-B2 Fused heterocyclic mescaline derivatives UGT2B7, CYP3A5, CYP2C19 DRD2 51/4885DRD3 78/4885DRD4 158/4885
US-12485181-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties CYP3A5, CYP2C19, CYP3A7 DRD2 520/4885DRD3 644/4885DRD4 420/4885
US-20240293560-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES CYP3A5, SPOP, CYP2C19 DRD2 662/4885DRD3 695/4885DRD4 598/4885
US-11298350-B2 Subcutaneous delivery of polymer conjugates of therapeutics agents CD44, CD47, LNPEP DRD2 4300/4885DRD3 4476/4885DRD4 4298/4885
US-11285147-B2 Neuroprotective agents for treatment of neurodegenerative diseases PARK7, SMN1; SMN2, CLN6 DRD2 283/4885DRD3 377/4885DRD4 192/4885
US-20260131012-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES CYP2C19, CYP2C9, CYP3A5 DRD2 949/4885DRD3 1124/4885DRD4 1293/4885
US-12383626-B2 Polyoxazoline-drug conjugates with novel pharmacokinetic properties CYP3A5, SPOP, CYP2C19 DRD2 662/4885DRD3 695/4885DRD4 598/4885
US-20240316208-A1 POLYOXAZOLINE-DRUG CONJUGATES WITH NOVEL PHARMACOKINETIC PROPERTIES CYP3A5, SPOP, CYP2C19 DRD2 662/4885DRD3 695/4885DRD4 598/4885
US-20220354841-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP DRD2 4521/4885DRD3 4643/4885DRD4 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.