Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428441 | 0.84 | KMT2A (0.46) | ALDH1A1KMT2ANPC1RAB9ACES2 | |
| SCHEMBL29428436 | 0.82 | HDAC1 (0.40) | MEN1KMT2AKEAP1NFE2L2KDM4E | |
| SCHEMBL28838323 | 0.81 | LMNA (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL28838325 | 0.77 | TACR1 (0.51) | MAPT | |
| SCHEMBL28556940 | 0.77 | CYP1A2 (0.54) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9154632 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL11795354 | 0.75 | ALDH1A1 (0.58) | ALDH1A1ATMMEN1KMT2ACRHBP | |
| SCHEMBL5470890 | 0.74 | ATM (0.52) | ALDH1A1SMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL7379932 | 0.73 | ATM (0.75) | ALDH1A1SMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL21800134 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256274-B | Method for preparing N-methyl-N-phenyl-2, 3-dibromo-3-substituted phenylpropionamide compound | 安徽理工大学 | 2022-02-15 | — | — | CN | disclosed |