SCHEMBL2942897

SCHEMBL2942897

CCN(CC)Cc1ccc(Br)c(CBr)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.50
TSHR P16473 2/20 0.44
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
PYCR1 P32322 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
NFKB1 P19838 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CCR5 P51681 1/20 0.40
LMNA P02545 1/20 0.40
BLM P54132 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288357 0.85 HRH3 (0.43) HRH3TSHRPYCR1CYP1A2CYP2D6
SCHEMBL27672757 0.83 TSHR (0.36) HRH3TSHRPYCR1CYP1A2CYP2D6
SCHEMBL2936648 0.82 TRPA1 (0.40) TSHRCYP1A2CYP2D6CYP2C19LMNA
SCHEMBL2290616 0.81 HDAC1 (0.42) HRH3TSHRHDAC8HDAC6PYCR1
SCHEMBL844393 0.81 HTR1A (0.49) HRH3HDAC8HDAC6PYCR1CCR5
SCHEMBL3483919 0.78 GABRA1 (0.38) HRH3TSHRHDAC8HDAC6PYCR1
SCHEMBL2293511 0.76 ALDH1A1 (0.33) CCR5ALDH1A1KMT2A
SCHEMBL2253179 0.74 HRH3 (0.70) HRH3HDAC8HDAC6PYCR1KDM4E
SCHEMBL3484617 0.74 CYP1A2 (0.37) HRH3TSHRPYCR1CYP1A2CYP2D6
SCHEMBL11269728 0.74 POLB (0.67) HRH3HDAC8HDAC6KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed
EP-2149545-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-03 EP disclosed