SCHEMBL2943008

SCHEMBL2943008

CCOC(CCN(C)C)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
DNM1 Q05193 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823290 0.85 ALDH1A1 (0.39) THRBLMNAHTR2AHRH1DNM1
SCHEMBL24246368 0.83
SCHEMBL11379275 0.77 THRB (0.35) THRBLMNAALDH1A1SMN1; SMN2
SCHEMBL5666168 0.76 THRB (0.50) THRBLMNA
SCHEMBL28411291 0.75 THRB (0.33) THRBLMNAHTR2AHRH1
SCHEMBL1254070 0.73 DNM1 (0.48) THRBDNM1CA12CA2CA3
SCHEMBL5545778 0.73
SCHEMBL20548483 0.73 THRB (0.32) THRBLMNA
SCHEMBL24484446 0.73 LMNA (0.42) THRBLMNAHTR2AHRH1
Hydrochloric Acid SCHEMBL11179561 0.73 THRB (0.32) THRBLMNAHTR2AHRH1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4280927-A A CHELATE OF HYDROCARBYL LITHIUM AND A DIALKYLAMINOALDEHYDE DIALKYL ACETAL THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-07-28 US claimed
WO-2025235840-A1 ECHINOCANDIN-LIKE AND BORON-CONTAINING ECHINOCANDIN COMPOUNDS AND THEIR USE AS AGROCHEMICAL FUNGICIDES 5METIS, INC. (US) 2025-11-13 WO disclosed
EP-4644377-A1 LIPID COMPOUND FOR GENE DELIVERY AND LIPID NANOPARTICLE COMPRISING SAME NANJING CYBERNAX BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2025-11-05 EP disclosed
CN-119219823-A Adsorbent with heparin slow release function, preparation method thereof and blood perfusion device 泉州师范学院 2024-12-31 CN disclosed
CN-110072865-B Pyrrolo-aromatic heterocyclic compounds, preparation method and medical application thereof 中国医药研究开发中心有限公司 2022-02-11 CN disclosed
CN-113121512-A Preparation method of quinazolinyl butene amide compound 江苏晶立信医药科技有限公司 2021-07-16 CN disclosed
EP-1489078-B1 BENZOFURAN DERIVATIVE MITSUBISHI TANABE PHARMA CORP (JP) 2010-01-06 EP disclosed
US-20090209511-A1 Benzofuran Derivatives KAWAGUCHI TAKAYUKI 2009-08-20 US disclosed
US-7531537-B2 Benzofuran derivative MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-05-12 US disclosed
CN-100439351-C Benzofuran derivative TANABE SEIYAKU CO (JP) 2008-12-03 CN disclosed
US-20050282808-A1 Benzofuran derivative MITSUBISHI TANABE PHARMA CORPORATION (JP) 2005-12-22 US disclosed
CN-1656086-A Benzofuran derivative TANABE SEIYAKU CO (JP) 2005-08-17 CN disclosed
EP-1489078-A1 BENZOFURAN DERIVATIVE Tanabe Seiyaku Co., Ltd. (JP) 2004-12-22 EP disclosed
US-4329439-A AN ORGANOLITHIUM COMPONENT, AND AN AMINO-ACETAL COMPONENT OF THE CATALYST THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-05-11 US disclosed
US-4280927-A A CHELATE OF HYDROCARBYL LITHIUM AND A DIALKYLAMINOALDEHYDE DIALKYL ACETAL THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282808-A1 Benzofuran derivative F12, F2, F11 THRB 3799/4885LMNA 3104/4885HTR2A 3664/4885
US-20090209511-A1 Benzofuran Derivatives F12, F2, F3 THRB 3790/4885LMNA 2928/4885HTR2A 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.