Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938315 | 0.86 | TDP1 (0.51) | POLBGPR35CASP6MAPTAPEX1 | |
| SCHEMBL2936968 | 0.83 | CSNK2A2 (0.44) | POLBGPR35CASP6MAPTAPEX1 | |
| SCHEMBL2936060 | 0.81 | ALDH1A1 (0.46) | POLBGPR35CASP6MAPTAPEX1 | |
| SCHEMBL5707256 | 0.81 | ALDH1A1 (0.59) | POLBGPR35CASP6MAPTAPEX1 | |
| SCHEMBL5712442 | 0.80 | CSNK2A2 (0.47) | POLBGPR35CASP6MAPTAPEX1 | |
| Nitrophenolate SCHEMBL11233778 | 0.79 | GPR35 (0.55) | GPR35ALDH1A1TDP1SMN1; SMN2HPGD | |
| SCHEMBL2931277 | 0.78 | MAPT (0.48) | MAPTALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL2940209 | 0.78 | MAPT (0.52) | MAPTCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| 2-Nitroaniline SCHEMBL20873614 | 0.78 | ALOX15 (0.58) | POLBGPR35MAPTALDH1A1TDP1 | |
| Nitrophenolate SCHEMBL28125078 | 0.78 | ALOX15 (0.58) | GPR35ALDH1A1SMN1; SMN2HPGDPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | claimed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | claimed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | disclosed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | disclosed |
| EP-1494995-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | disclosed |
| WO-2003087034-A1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | ALPP, TYR, RB1 | POLB 3840/4885GPR35 2415/4885CASP6 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.