SCHEMBL29433737

SCHEMBL29433737

N#CC(C#N)=c1ccc(=C(C#N)C#N)cc1.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MCL1 Q07820 1/20 0.58
▸ ALDH1A1 P00352 8/20 0.43
▸ CYP1A2 P05177 6/20 0.43
▸ HPGD P15428 5/20 0.43
▸ HSD17B10 Q99714 4/20 0.43
▸ THRB P10828 1/20 0.43
▸ MAOA P21397 2/20 0.35
▸ ERBB2 P04626 1/20 0.35
▸ FYN P06241 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ TSHR P16473 2/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ CYP1A1 P04798 1/20 0.35
▸ CYP1B1 Q16678 1/20 0.35
▸ KDM4E B2RXH2 5/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ MAPT P10636 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27847841 0.82 ALDH1A1 (0.55) MCL1ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL8320177 0.80 MCL1 (0.53) MCL1ALDH1A1CYP1A2HPGDHSD17B10
Cyanate SCHEMBL22436247 0.80 ALDH1A1 (0.52) MCL1ALDH1A1CYP1A2HPGDHSD17B10
Water SCHEMBL30762258 0.76 ALDH1A1 (0.67) MCL1ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL28137055 0.76 MAPT (0.35) MCL1ALDH1A1THRBTSHRKDM4E
Water SCHEMBL4564698 0.76 ALDH1A1 (0.67) MCL1ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL28891826 0.75 ALDH1A1 (0.52) MCL1ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL8054171 0.74 MEN1 (0.34) MCL1ALDH1A1THRBTSHRKDM4E
SCHEMBL1051092 0.74 MEN1 (0.34) MCL1ALDH1A1THRBTSHRKDM4E
SCHEMBL1501109 0.74 MEN1 (0.34) MCL1ALDH1A1THRBTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114004825-A Water surface oil spill detection algorithm based on infrared sequence image 南通智能感知研究院 2022-02-01 — — CN claimed
EP-4706525-A2 ELECTROMECHANICAL PILL DEVICE WITH LOCALIZATION CAPABILITIES BT Bidco, Inc. (US) 2026-03-11 — — EP disclosed
US-20260033738-A1 Electromechanical Pill Device with Localization Capabilities BT BIDCO INC (US) 2026-02-05 — — US disclosed
EP-3799776-B1 ELECTROMECHANICAL PILL DEVICE WITH LOCALIZATION CAPABILITIES BT BIDCO INC (US) 2025-11-26 — — EP disclosed
US-12446794-B2 Electromechanical pill device with localization capabilities BT BIDCO, INC. (US) 2025-10-21 — — US disclosed
CN-119030552-A Communication method, device, storage medium and chip 北京小米移动软件有限公司 2024-11-26 — — CN disclosed
US-20240358273-A1 Electromechanical Pill Device with Localization Capabilities GLAS USA LLC 2024-10-31 — — US disclosed
EP-3512938-B1 RECOMBINANT CARDIOMYOCYTES AND CARDIOMYOCYTE CELL LINES EXPRESSING HERG UNIV ALBERTA (CA) 2024-08-28 — — EP disclosed
US-20240273727-A1 GENERATING IMAGE-BASED BIOMARKERS FOR ALZHEIMER'S DISEASE AND RELATED DEMENTIAS Siemens Healthineers Ag (DE) 2024-08-15 — — US disclosed
EP-4414998-A1 GENERATING IMAGE-BASED BIOMARKERS FOR ALZHEIMER'S DISEASE AND RELATED DEMENTIAS Siemens Healthineers AG (DE) 2024-08-14 — — EP disclosed
US-12053271-B2 Electromechanical pill device with localization capabilities BIORA THERAPEUTICS, INC. (US) 2024-08-06 — — US disclosed
CN-117977714-A Power control method, device, storage medium and processor 广东电网有限责任公司 2024-05-03 — — CN disclosed
US-20240066144-A1 BONE MARROW-, RETICULOENDOTHELIAL SYSTEM-, AND/OR LYMPH NODE-TARGETED RADIOLABELED LIPOSOMES AND METHODS OF THEIR DIAGNOSTIC AND THERAPEUTIC USE MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-02-29 — — US disclosed
US-20230235290-A1 RECOMBINANT CARDIOMYOCYTES AND CARDIOMYOCYTE CELL LINES EXPRESSING HERG UNIV ALBERTA (CA) 2023-07-27 — — US disclosed
US-11633502-B2 Bone marrow-, reticuloendothelial system-, and/or lymph node-targeted radiolabeled liposomes and methods of their diagnostic and therapeutic use MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2023-04-25 — — US disclosed
US-11591570-B2 Recombinant cardiomyocytes and cardiomyocyte cell lines expressing hERG THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2023-02-28 — — US disclosed
CN-114004825-A Water surface oil spill detection algorithm based on infrared sequence image 南通智能感知研究院 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235290-A1 RECOMBINANT CARDIOMYOCYTES AND CARDIOMYOCYTE CELL LINES EXPRESSING HERG TNNI3, MYLK2, TNNT2 MCL1 982/4885ALDH1A1 3827/4885CYP1A2 3515/4885
US-11633502-B2 Bone marrow-, reticuloendothelial system-, and/or lymph node-targeted radiolabeled liposomes and methods of their diagnostic and therapeutic use BST2, LIPG, LDLR MCL1 22/4885ALDH1A1 1934/4885CYP1A2 1187/4885
US-20240066144-A1 BONE MARROW-, RETICULOENDOTHELIAL SYSTEM-, AND/OR LYMPH NODE-TARGETED RADIOLABELED LIPOSOMES AND METHODS OF THEIR DIAGNOSTIC AND THERAPEUTIC USE BST2, LIPG, LDLR MCL1 18/4885ALDH1A1 1920/4885CYP1A2 1322/4885
US-11591570-B2 Recombinant cardiomyocytes and cardiomyocyte cell lines expressing hERG KCNJ2, KCNH2, KCNE1 MCL1 1156/4885ALDH1A1 2059/4885CYP1A2 1328/4885
US-20260033738-A1 Electromechanical Pill Device with Localization Capabilities MLNR, PIEZO1, GIPR MCL1 4735/4885ALDH1A1 1073/4885CYP1A2 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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