SCHEMBL2943426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2952835	0.90	MEN1 (0.44)	CYP1A2CYP2C19CYP2C9NPC1RAB9A
	SCHEMBL14570801	0.89	TSHR (0.54)	CYP2C19NPC1RAB9AXDHMEN1
	SCHEMBL2951883	0.88	ADORA3 (0.45)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2950844	0.87	CYP1A2 (0.48)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2948823	0.86	CYP1A2 (0.47)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2954483	0.81	LMNA (0.49)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2953434	0.77	MEN1 (0.46)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2953519	0.75	CYP3A4 (0.47)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9
	SCHEMBL2953069	0.75	PDE4B (0.44)	CYP1A2CYP2D6NPC1RAB9ANFKB1
	SCHEMBL2945524	0.75	KMT2A (0.43)	CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.