SCHEMBL2943524

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2950530	0.90	TP53 (0.43)	USP2TSHRRAB9ANPC1TP53
	SCHEMBL2945514	0.81	RAB9A (0.46)	RAB9ANPC1MAPTLMNAKDM4E
	SCHEMBL2951883	0.81	ADORA3 (0.45)	TSHRRAB9ANPC1TP53MAPT
	SCHEMBL2945524	0.80	KMT2A (0.43)	TSHRRAB9ANPC1MAPTLMNA
	SCHEMBL2950536	0.79	RAB9A (0.44)	TSHRRAB9ANPC1MAPTLMNA
	SCHEMBL2948828	0.76	RAB9A (0.42)	USP2RAB9ANPC1TP53MAPT
	SCHEMBL2952951	0.74	RAB9A (0.46)	USP2TSHRRAB9ANPC1HPGD
	SCHEMBL2950844	0.71	CYP1A2 (0.48)	USP2TSHRRAB9ANPC1TP53
	SCHEMBL2944090	0.70	CCNC (0.46)	TSHRRAB9ANPC1MAPTLMNA
	SCHEMBL2943426	0.70	CYP1A2 (0.49)	USP2TSHRRAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.