SCHEMBL29436002

SCHEMBL29436002

Nc1ncnc2c1ncn2N1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.55
▸ ADORA2A P29274 2/20 0.55
▸ ADORA2B P29275 2/20 0.55
▸ ADORA1 P30542 2/20 0.55
▸ DPP4 P27487 1/20 0.55
▸ MEN1 O00255 1/20 0.55
▸ SLC28A1 O00337 1/20 0.55
▸ MAP3K7 O43318 1/20 0.55
▸ SLC28A2 O43868 1/20 0.55
▸ GAPDH P04406 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ STAT6 P42226 1/20 0.55
▸ PI4KA P42356 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ PI4K2B Q8TCG2 1/20 0.55
▸ DOT1L Q8TEK3 1/20 0.55
▸ SLC29A1 Q99808 1/20 0.55
▸ PI4K2A Q9BTU6 1/20 0.55
▸ SLC28A3 Q9HAS3 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30487166 0.84 ADORA1 (0.41) ADORA3ADORA2AADORA2BADORA1MAPK1
SCHEMBL250995 0.79 ADORA3 (0.51) ADORA3ADORA2AADORA2BADORA1DPP4
SCHEMBL25334955 0.79 P2RX3 (0.63) SMN1; SMN2ALDH1A1
SCHEMBL8632632 0.77 ADORA3 (0.51) ADORA3ADORA2AADORA2BADORA1DPP4
SCHEMBL1276059 0.75 PNP (0.47) ADORA3MEN1KMT2ASMN1; SMN2ALDH1A1
Adenosine SCHEMBL23420216 0.71 ADORA3 (1.00) ADORA3ADORA2AADORA2BADORA1DPP4
Adenosine SCHEMBL4403412 0.71 ADORA3 (1.00) ADORA3ADORA2AADORA2BADORA1DPP4
Adenosine SCHEMBL23804425 0.71 ADORA3 (1.00) ADORA3ADORA2AADORA2BADORA1DPP4
Adenosine SCHEMBL2028876 0.71 ADORA3 (1.00) ADORA3ADORA2AADORA2BADORA1DPP4
Vidarabine SCHEMBL110914 0.71 ADORA3 (1.00) ADORA3ADORA2AADORA2BADORA1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12338464-B2 Clonal strains of attenuated vaccinia viruses and methods of use thereof GENELUX CORPORATION (US) 2025-06-24 — — US disclosed
CN-114751950-B Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2025-04-18 — — CN disclosed
CN-118304290-A Application of Albanol B in preparation of dual-target anti-gout enzyme inhibitor 兰州理工大学 2024-07-09 — — CN disclosed
CN-111194318-B Solid forms of compounds for modulating kinases OPNA生物公司 2023-06-09 — — CN disclosed
US-20230008052-A1 CLONAL STRAINS OF ATTENUATED VACCINIA VIRUSES AND METHODS OF USE THEREOF GENELUX CORPORATION 2023-01-12 — — US disclosed
US-20220340613-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE IMMUNESENSOR THERAPEUTICS, INC. 2022-10-27 — — US disclosed
EP-3429596-B1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE IMMUNE SENSOR LLC (US) 2022-08-31 — — EP disclosed
CN-114929288-A Synthetic modified RNA and uses thereof 西奈山伊坎医学院 2022-08-19 — — CN disclosed
CN-114751950-A Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2022-07-15 — — CN disclosed
CN-114450265-A Cationic lipids and uses thereof 菲克特生物科学股份有限公司 2022-05-06 — — CN disclosed
US-11299512-B2 Cyclic di-nucleotide compounds and methods of use IMMUNESENSOR THERAPEUTICS, INC. (US) 2022-04-12 — — US disclosed
CN-109475570-B Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2022-04-01 — — CN disclosed
CN-114230625-A Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2022-03-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299512-B2 Cyclic di-nucleotide compounds and methods of use CGAS, PDE7A, PDE11A ADORA3 246/4885ADORA2A 116/4885ADORA2B 255/4885
US-20220340613-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE CGAS, PDE7A, PDE11A ADORA3 246/4885ADORA2A 116/4885ADORA2B 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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