Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074161 | 1.00 | CHEK1 (0.37) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL21074098 | 0.94 | CHEK1 (0.40) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL21074243 | 0.85 | CHEK1 (0.41) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL29116347 | 0.85 | TDO2 (0.32) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL20496063 | 0.83 | MAPT (0.47) | CHEK1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL11947037 | 0.82 | L3MBTL1 (0.42) | MAPK14ALDH1A1KDM4ELMNATHRB | |
| SCHEMBL29966432 | 0.82 | L3MBTL1 (0.42) | MAPK14ALDH1A1KDM4ELMNATHRB | |
| SCHEMBL18748014 | 0.81 | LMNA (0.43) | ALDH1A1KDM4EHTTLMNAADORA1 | |
| SCHEMBL21074220 | 0.81 | PGR (0.38) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL29437698 | 0.81 | PGR (0.38) | CHEK1ABL1PDGFRBPDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375779-B1 | 2,3-DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL AND LIGHT TRANSMITTER USING THE SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-108137554-B | Dicyanopyrazine compound, light-emitting material, light-emitting element using the light-emitting material, and method for producing 2, 5-dicyano-3, 6-dihalopyrazine | 国立大学法人九州大学 | 2022-03-18 | — | — | CN | disclosed |