Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | GLA | P06280 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442266 | 0.88 | ALDH1A1 (0.80) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL22208219 | 0.83 | SQOR (0.77) | KDM4EALDH1A1NPSR1TDP1GLA | |
| SCHEMBL29442295 | 0.83 | SQOR (0.77) | KDM4EALDH1A1NPSR1TDP1GLA | |
| SCHEMBL22215730 | 0.82 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL22215646 | 0.82 | ALDH1A1 (0.82) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL29442491 | 0.82 | SQOR (0.75) | KDM4EALDH1A1NPSR1GLAGAA | |
| SCHEMBL22215651 | 0.81 | KDM4E (0.80) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL22215728 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL29442321 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL22215727 | 0.80 | ALDH1A1 (0.77) | KDM4EALDH1A1HPGDNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | DREXEL UNIVERSITY | 2022-03-31 | — | — | US | claimed |
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | DREXEL UNIVERSITY | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | SQOR, QSOX1, KEAP1 | KDM4E 316/4885ALDH1A1 411/4885HPGD 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.