SCHEMBL2944444

SCHEMBL2944444

Nc1ccc(C(CO)CO)c(N)c1CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20210937 0.78 TDP1 (0.33)
SCHEMBL460054 0.75 TDP1 (0.38)
SCHEMBL5551242 0.75
SCHEMBL22499986 0.72 GAA (0.39)
SCHEMBL754268 0.72 TDP1 (0.30)
SCHEMBL21753755 0.72 GABRA1 (0.44)
SCHEMBL4249599 0.69 TDP1 (0.33)
SCHEMBL5551238 0.68
SCHEMBL6241968 0.68 MAPT (0.44)
SCHEMBL28856679 0.67 CA2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765267-B1 INITIAL PHENYLPROPANEDIOL DYE PRODUCTS HENKEL AG & CO KGAA (DE) 2010-01-06 EP disclosed
EP-1765267-A1 INITIAL PHENYLPROPANEDIOL DYE PRODUCTS Henkel Kommanditgesellschaft auf Aktien (DE) 2007-03-28 EP disclosed
WO-2006002712-A1 INITIAL PHENYLPROPANEDIOL DYE PRODUCTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-01-12 WO disclosed