Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211016 | 0.87 | HTR1A (0.49) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL3669746 | 0.85 | L3MBTL1 (0.48) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL19235306 | 0.85 | TNKS (0.47) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL19235261 | 0.85 | ALDH1A1 (0.47) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL19235264 | 0.82 | ADRA1B (0.47) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL4952229 | 0.82 | OPRL1 (0.60) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL20783508 | 0.82 | DRD2 (0.49) | OPRL1OPRM1OPRK1OPRD1TSHR | |
| SCHEMBL3668112 | 0.81 | TNKS (0.50) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL20783323 | 0.81 | ALDH1A1 (0.50) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL19235362 | 0.81 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884096-B | Spiroindolinones as DDR1 inhibitors | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | disclosed |