Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714073 | 0.95 | FAAH (0.34) | FAAHMGLLBRD4TSHRNPSR1 | |
| SCHEMBL29444554 | 0.80 | TSHR (0.56) | BRD4TSHRNPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL8448754 | 0.78 | FAAH (0.47) | FAAHMGLLBRD4TSHRNPSR1 | |
| SCHEMBL758556 | 0.77 | FAAH (0.36) | FAAHMGLLBRD4TUBB4ATUBB | |
| SCHEMBL30062492 | 0.76 | TSHR (0.51) | BRD4TSHRNPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL30928284 | 0.75 | FAAH (0.32) | FAAHMGLLBRD4TUBB4ATUBB | |
| SCHEMBL798141 | 0.73 | FAAH (0.41) | FAAHMGLLBRD4TUBB4ATUBB | |
| SCHEMBL1984416 | 0.73 | TUBB4A (0.38) | FAAHMGLLBRD4TSHRNPSR1 | |
| SCHEMBL25434842 | 0.72 | FAAH (0.38) | FAAHMGLLBRD4TSHRNPSR1 | |
| SCHEMBL22123254 | 0.72 | CHRNB2 (0.40) | FAAHMGLLBRD4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109152771-B | Use of 2-substituted indazoles for the treatment and prevention of autoimmune diseases | 拜耳医药股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-110305109-B | Novel substituted indazoles, method for the production thereof, pharmaceutical preparations containing same, and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2022-04-08 | — | — | CN | disclosed |