Sugi Predict

Sugi Predict / Compounds / SCHEMBL758556

SCHEMBL758556

SCHEMBL758556

CN(C)[PH](On1nnc2cccnc21)(N(C)C)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 3/20 0.36
▸ MGLL Q99685 3/20 0.36
▸ TUBB4A P04350 1/20 0.34
▸ TUBB P07437 1/20 0.34
▸ TUBA3C P0DPH7 1/20 0.34
▸ TUBA1B P68363 1/20 0.34
▸ TUBA4A P68366 1/20 0.34
▸ TUBB4B P68371 1/20 0.34
▸ TUBB3 Q13509 1/20 0.34
▸ TUBB2A Q13885 1/20 0.34
▸ TUBB8 Q3ZCM7 1/20 0.34
▸ TUBA3E Q6PEY2 1/20 0.34
▸ TUBA1A Q71U36 1/20 0.34
▸ TUBA1C Q9BQE3 1/20 0.34
▸ TUBB6 Q9BUF5 1/20 0.34
▸ TUBB2B Q9BVA1 1/20 0.34
▸ TUBB1 Q9H4B7 1/20 0.34
▸ BRD4 O60885 1/20 0.32
▸ RAB9A P51151 2/20 0.31
▸ NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678889 0.79 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL29444556 0.77 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL798141 0.77 FAAH (0.41) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL1984416 0.77 TUBB4A (0.38) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL23629284 0.77 FAAH (0.35) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL58561 0.76 TSHR (0.49) RAB9ANPC1
SCHEMBL15697618 0.76 FAAH (0.39) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL757020 0.76 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL31494777 0.76 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL29639612 0.76 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118851929-A Preparation method of ELACESTRANT key intermediate 浙江科聚生物医药有限公司 2024-10-29 — — CN claimed
EP-1436284-B1 SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE SCHERING CORP (US) 2005-08-03 — — EP claimed
CN-118851929-A Preparation method of ELACESTRANT key intermediate 浙江科聚生物医药有限公司 2024-10-29 — — CN disclosed
US-20200360532-A1 PROCESS FOR THE PREPARATION OF DRUG LINKER COMPOUNDS SEAGEN INC. 2020-11-19 — — US disclosed
WO-2020190757-A1 IMPROVED PROCESSES FOR THE PREPARATION OF SEMAGLUTIDE NOVETIDE LTD. (IL) 2020-09-24 — — WO disclosed
EP-3221342-A1 SYNTHESIS OF GLP-1 PEPTIDES Novetide Ltd. (IL) 2017-09-27 — — EP disclosed
US-9487592-B2 Immobilization substrate and method for producing the same FUJIFILM CORPORATION (JP) 2016-11-08 — — US disclosed
WO-2016046753-A1 SYNTHESIS OF GLP-1 PEPTIDES NOVETIDE, LTD. (IL) 2016-03-31 — — WO disclosed
EP-2956437-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS Centre de Cooperation Internationale en Recherche Agronomique pour le Developpement (FR) 2015-12-23 — — EP disclosed
US-20150183818-A1 PROCESS FOR PREPARING DIASTEREOMERICALLY ENRICHED PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-07-02 — — US disclosed
US-20150024392-A1 METHOD FOR PRODUCING A BIOSENSOR FUJIFILM CORPORATION (JP) 2015-01-22 — — US disclosed
US-20090140209-A1 PROCESS FOR PRODUCING A CARRIER FUJIFILM CORPORATION (JP) 2009-06-04 — — US disclosed
US-20090081427-A1 METHOD FOR PRODUCING AN IMMOBILIZATION SUBSTRATE AND IMMOBILIZATION SUBSTRATE PRODUCED BY THE METHOD FUJIFILM CORPORATION (JP) 2009-03-26 — — US disclosed
US-20090062515-A1 METHOD FOR PURIFYING BIOACTIVE SUBSTANCES FUJIFILM CORPORATION (JP) 2009-03-05 — — US disclosed
US-20090016933-A1 CARRIER, PROCESS FOR PRODUCING SAME, BIOREACTOR, AND CHIP FOR SURFACE PLASMON RESONANCE ANALYSIS FUJIFILM CORPORATION (JP) 2009-01-15 — — US disclosed
US-20080188010-A1 Non-specific adsorption on oxide films FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080187977-A1 METHOD FOR PRODUCTION OF PHYSIOLOGICALLY ACTIVE SUBSTANCE-IMMOBILIZED SUBSTRATE FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080187462-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE-IMMOBILIZED SUBSTRATE FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080090306-A1 METHOD FOR IMMOBILIZING BIOMOLECULES FUJIFILM CORPORATION (JP) 2008-04-17 — — US disclosed
US-20070258866-A1 Method for producing a biosensor FUJIFILM CORPORATION 2007-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062515-A1 METHOD FOR PURIFYING BIOACTIVE SUBSTANCES BMP2, BMP1, BMP4 FAAH 1743/4885MGLL 1142/4885TUBB4A 3345/4885
US-20150183818-A1 PROCESS FOR PREPARING DIASTEREOMERICALLY ENRICHED PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS SAMHD1, TYMP, PNP FAAH 4545/4885MGLL 4128/4885TUBB4A 2515/4885
US-20200360532-A1 PROCESS FOR THE PREPARATION OF DRUG LINKER COMPOUNDS FPGS, PAICS, DHFR FAAH 2113/4885MGLL 4814/4885TUBB4A 1835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.