Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE12 | Q6L8Q7 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16733123 | 0.55 | ALDH1A1 (0.39) | RAB9AMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28703164 | 0.55 | SLC6A2 (0.45) | PRCPKCNH2 | |
| SCHEMBL25330818 | 0.54 | MDM2 (0.40) | PRCPKCNH2MAPTALDH1A1 | |
| SCHEMBL25334667 | 0.54 | MDM2 (0.40) | PRCPKCNH2MAPTALDH1A1 | |
| SCHEMBL12521045 | 0.54 | MEN1 (0.45) | — | |
| SCHEMBL2296318 | 0.54 | GRIN2B (0.51) | MAPTALDH1A1GAA | |
| SCHEMBL2294991 | 0.54 | GRIN2B (0.51) | MAPTALDH1A1GAA | |
| SCHEMBL7977026 | 0.54 | HTR1A (0.58) | KCNH2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7977029 | 0.54 | HTR1A (0.58) | KCNH2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2296518 | 0.53 | PKM (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213354-A | Preparation method of trans-2- (substituted phenyl) -3-hydroxymethyl morpholine | 上海皓元生物医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |