Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049216 | 0.84 | KDM4E (0.33) | KDM4ESHBG | |
| SCHEMBL2944734 | 0.82 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL30389113 | 0.82 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL28894056 | 0.77 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL29371482 | 0.76 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL673358 | 0.76 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL14790330 | 0.75 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL4387585 | 0.75 | NPC1 (0.37) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL6330928 | 0.75 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL19305660 | 0.74 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8529921-B2 | Polyamide-5 compounds in cosmetic preparations | BEIERSDORF AG (DE) | 2013-09-10 | — | — | US | disclosed |
| US-20110268674-A1 | POLYAMIDE-5 COMPOUNDS IN COSMETIC PREPARATIONS | BEIERSDORF AG (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110014139-A1 | SUN PROTECTION COMPOSITIONS | BAYER MATERIAL SCIENCE AG (DE) | 2011-01-20 | — | — | US | disclosed |
| US-20090203817-A1 | STABILIZED SPANDEX COMPOSITIONS | CYTEC TECHNOLOGY CORP. | 2009-08-13 | — | — | US | disclosed |
| JP-2009169306-A | PROTECTION FILM FOR POLARIZING PLATE, AND POLARIZING PLATE | NIPPON ZEON CO LTD | 2009-07-30 | — | — | JP | disclosed |
| US-5635553-A | MIXTURE OF POLYAMIDES, ETHYLENE-VINYL ALCOHOL COPOLYMERS, POLYALKYLENE GLYCOL; PACKAGING FILMS; REDUCED FISH EYE GEL FORMATION | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014139-A1 | SUN PROTECTION COMPOSITIONS | ERCC4, ERCC1, ERCC5 | NPC1 2965/4885RAB9A 3194/4885LMNA 313/4885 |
| US-20110268674-A1 | POLYAMIDE-5 COMPOUNDS IN COSMETIC PREPARATIONS | CUTA, PLIN5, PGA5 | NPC1 3523/4885RAB9A 2961/4885LMNA 99/4885 |
| US-20090203817-A1 | STABILIZED SPANDEX COMPOSITIONS | SMCHD1, SMC1A, SI | NPC1 807/4885RAB9A 2836/4885LMNA 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.