Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL628931 | 1.00 | LMNA (0.40) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL28359850 | 0.97 | LMNA (0.38) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL29038532 | 0.97 | LMNA (0.38) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL28238015 | 0.94 | LMNA (0.36) | LMNAFDPSGRM4CA2 | |
| Methyl Phosphonate SCHEMBL518187 | 0.90 | CA2 (0.50) | LMNAFDPSGRM4CA2KDM4E | |
| SCHEMBL28315800 | 0.88 | LMNA (0.36) | LMNAFDPSGRM4CA2 | |
| Phosphoramidic Acid SCHEMBL29140204 | 0.88 | FDPS (0.41) | LMNAFDPSGRM4CA2 | |
| SCHEMBL7128570 | 0.85 | KDM4E (0.40) | LMNAFDPSGRM4KDM4EMMP2 | |
| SCHEMBL29286249 | 0.84 | FDPS (0.36) | LMNAFDPSGRM4 | |
| SCHEMBL28151916 | 0.84 | LMNA (0.32) | LMNAFDPSTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213462-A | O-phenylenedioxy bis-neopentyl glycol phosphate and its synthesis method | 江苏三吉利化工股份有限公司 | 2022-03-22 | — | — | CN | disclosed |