Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29447765 | 1.00 | LMNA (0.40) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL28359850 | 0.97 | LMNA (0.38) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL29038532 | 0.97 | LMNA (0.38) | LMNAFDPSGRM4CA2KDM4E | |
| Phosphoric Acid SCHEMBL28238015 | 0.94 | LMNA (0.36) | LMNAFDPSGRM4CA2 | |
| Methyl Phosphonate SCHEMBL518187 | 0.90 | CA2 (0.50) | LMNAFDPSGRM4CA2KDM4E | |
| SCHEMBL28315800 | 0.88 | LMNA (0.36) | LMNAFDPSGRM4CA2 | |
| Phosphoramidic Acid SCHEMBL29140204 | 0.88 | FDPS (0.41) | LMNAFDPSGRM4CA2 | |
| SCHEMBL7128570 | 0.85 | KDM4E (0.40) | LMNAFDPSGRM4KDM4EMMP2 | |
| SCHEMBL29286249 | 0.84 | FDPS (0.36) | LMNAFDPSGRM4 | |
| SCHEMBL28151916 | 0.84 | LMNA (0.32) | LMNAFDPSTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221972805-U | Spliced concrete precast slab | 贵州省织金县华通混凝土有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-221778860-U | Heat insulation assembly building heat preservation plate | 大连西罗丹建筑工程有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-111501375-B | Flame-retardant modified asphalt waterproof coiled material and preparation method thereof | 青岛悦浪建筑技术有限责任公司 | 2023-06-09 | — | — | CN | claimed |
| CN-113881149-A | Low-hardness V0-grade flame-retardant ethylene propylene rubber material | 安徽京鸿密封件技术有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-109585916-B | Flame-retardant polymer solid electrolyte material, electrolyte membrane and application thereof | 吉林师范大学 | 2021-04-20 | — | — | CN | claimed |
| CN-111501375-A | Flame-retardant modified asphalt waterproof coiled material and preparation method thereof | 青岛悦浪建筑技术有限责任公司 | 2020-08-07 | — | — | CN | claimed |
| CN-109585916-A | A kind of flame-retardant polymer solid electrolyte material and its dielectric film and application | 吉林师范大学 | 2019-04-05 | — | — | CN | claimed |
| EP-2420553-A1 | Environmentally-Friendly Lubricant Compositions | Afton Chemical Corporation (US) | 2012-02-22 | — | — | EP | claimed |
| CN-102002770-B | Preparation method of halogen-free flame retardant high-intensity polyvinyl alcohol fibers | UNIV SICHUAN | 2012-01-25 | — | — | CN | claimed |
| CN-101845208-B | Unsaturated polyester resin composite material and preparation method thereof | UNIV XIAMEN | 2011-09-28 | — | — | CN | claimed |
| CN-101265348-B | Nano barium tungstate synergism expansibility flame-proof polypropylene and preparation method thereof | NEIJING INST OF TECHNOLOGY | 2010-09-08 | — | — | CN | claimed |
| US-20100152078-A1 | ENVIRONMENTALLY-FRIENDLY LUBRICANT COMPOSITIONS | AFTON CHEMICAL CORPORATION | 2010-06-17 | — | — | US | claimed |
| EP-2025737-A1 | Environmentally-friendly fuel compositions | Afton Chemical Corporation (US) | 2009-02-18 | — | — | EP | claimed |
| US-20090031614-A1 | Environmentally-Friendly Fuel Compositions | AFTON CHEMICAL CORPORATION | 2009-02-05 | — | — | US | claimed |
| EP-2017329-A1 | Environmentally-Friendly Lubricant Compositions | Afton Chemical Corporation (US) | 2009-01-21 | — | — | EP | claimed |
| US-20080305972-A1 | LUBRICANT COMPOSITIONS | AFTON CHEMICAL CORPORATION | 2008-12-11 | — | — | US | claimed |
| US-20080274921-A1 | Environmentally-Friendly Lubricant Compositions | AFTON CHEMICAL CORPORATION | 2008-11-06 | — | — | US | claimed |
| CN-101265348-A | Nano barium tungstate synergism expansibility flame-proof polypropylene and preparation method thereof | NEIJING INST OF TECHNOLOGY (CN) | 2008-09-17 | — | — | CN | claimed |
| EP-1785470-A2 | Composition comprising a sulfur-containing, phosphorus-containing compound, and/or its salt, and uses thereof | Afton Chemical Corporation (US) | 2007-05-16 | — | — | EP | claimed |
| EP-0132265-B1 | METHOD FOR MANUFACTURING CELLULAR PRODUCTS AND LAMINATES BASED ON FURAN PREPOLYMERS | ASHLAND-AVEBENE, société anonyme (FR) | 1989-12-06 | — | — | EP | claimed |