SCHEMBL29448798

SCHEMBL29448798

O=[PH]1Oc2c(Cl)cccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.36
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
ELANE P08246 1/20 0.30
NOTUM Q6P988 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NSD2 O96028 1/20 0.30
BCHE P06276 1/20 0.30
DAO P14920 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8570213 1.00 AHR (0.36) AHRNPC1TP53HPGDRAB9A
SCHEMBL8406911 0.81 ALDH1A1 (0.33) AHRALDH1A1NPSR1
SCHEMBL30165037 0.79 MYC (0.33) NPC1RAB9ASMN1; SMN2TSHRNOTUM
SCHEMBL30165005 0.79 HNF4A (0.33) HPGDCYP2A6TSHRLMNAALDH1A1
SCHEMBL17201415 0.79 HNF4A (0.33) HPGDCYP2A6TSHRLMNAALDH1A1
SCHEMBL28371515 0.77 NPC1 (0.35) NPC1HPGDRAB9ASMN1; SMN2TSHR
SCHEMBL30594715 0.76 GABRA1 (0.34) ELANE
SCHEMBL29035096 0.76 AHR (0.34) AHRNPC1TP53HPGDRAB9A
SCHEMBL2434723 0.75 DPP4 (0.38) HPGDTSHRLMNAKMT2A
SCHEMBL30594732 0.75 DPP4 (0.38) HPGDTSHRLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269846-B Transparent thermoplastic resin composition, method for producing same, molded article, and method for producing molded article 东丽株式会社 2024-03-22 CN disclosed
CN-114269846-A Transparent thermoplastic resin composition, method for producing same, molded article obtained by molding transparent thermoplastic resin composition, and method for producing molded article 东丽株式会社 2022-04-01 CN disclosed