SCHEMBL29450177

SCHEMBL29450177

Cc1cc(C)c(O)c(CN)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
SHBG P04278 1/20 0.41
AMY1A P0DUB6 1/20 0.39
HSPA5 P11021 1/20 0.39
CA2 P00918 2/20 0.39
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
SELE P16581 1/20 0.39
CA1 P00915 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560610 1.00 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL15966095 0.88 AMY1A (0.48) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL11675060 0.82 CYP3A4 (0.41) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL10362981 0.81 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL69707 0.81 AMY1A (0.57) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL12209717 0.80 ALDH1A1 (0.40) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL27583609 0.80 SHBG (0.44) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL17426912 0.80 SHBG (0.53) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL28165477 0.79 ALDH1A1 (0.44) ALDH1A1LMNAKDM4EGAAMAPT
SCHEMBL4456468 0.79 AMY1A (0.61) ALDH1A1LMNAKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316101-B Metallocene catalyst, preparation method and application thereof in catalyzing olefin polymerization 万华化学集团股份有限公司 2023-10-17 CN disclosed
CN-114316101-A Metallocene catalyst, preparation method and application thereof in catalyzing olefin polymerization 万华化学集团股份有限公司 2022-04-12 CN disclosed