SCHEMBL2945245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2949496	0.87	KDM4E (0.39)	PTPN1
	SCHEMBL2945759	0.83	SIRT2 (0.39)	PTPN1ENPP2CA12CA9ESR1
	SCHEMBL2946384	0.83	SIRT2 (0.44)	ENPP2CA12CA9ESR1CA1
	SCHEMBL2943810	0.82	THRA (0.44)	PTPN1ENPP2CA12CA9CA1
	SCHEMBL2944827	0.81	ENPP2 (0.48)	PTPN1ENPP2CA12CA9ESR1
	SCHEMBL2946099	0.81	TSHR (0.46)	PTPN1KDR
	SCHEMBL2945320	0.77	PPARG (0.46)	PTPN1F2RL3
	SCHEMBL2946398	0.77	FFAR1 (0.39)	PTPN1CA12CA9CA1CA2
	SCHEMBL2951909	0.75	F2RL3 (0.42)	PTPN1ENPP2CA12CA9CA1
	SCHEMBL2948596	0.73	MEN1 (0.42)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.