Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945263 | 1.00 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DMTNR1A | |
| SCHEMBL7759160 | 0.84 | KDM1A (0.38) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL14959965 | 0.78 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL13372976 | 0.78 | MAPT (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL88322 | 0.78 | ALDH1A1 (0.46) | MTNR1AMTNR1BALDH1A1KMT2AMAPT | |
| SCHEMBL24098444 | 0.77 | ALDH1A1 (0.33) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL44266 | 0.76 | MTNR1A (0.42) | PDE4APDE4BPDE4CPDE4DMTNR1A | |
| SCHEMBL183824 | 0.74 | KDM1A (0.42) | MTNR1AMTNR1BALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL2807530 | 0.73 | KMT2A (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL2807525 | 0.73 | KMT2A (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535947-B1 | Diorganosiloxane derivatives containing a 4,4-diarylbutadiene moiety, sunscreen compositions containing them and their uses | OREAL (FR) | 2010-01-06 | — | — | EP | disclosed |
| EP-1535947-A1 | Diorganosiloxane derivatives containing a 4,4-diarylbutadiene moiety, sunscreen compositions containing them and their uses | L'OREAL (FR) | 2005-06-01 | — | — | EP | disclosed |