Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | PGR | P06401 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726513 | 0.86 | RAB9A (0.66) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL20157316 | 0.85 | MAPT (0.61) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL7928540 | 0.84 | CYP1A2 (0.52) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL20157317 | 0.84 | NPC1 (0.58) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL3224251 | 0.83 | NPC1 (0.81) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| Oxybenzone SCHEMBL15551 | 0.83 | HPGD (1.00) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL3480945 | 0.83 | ALDH1A1 (0.71) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| Oxybenzone SCHEMBL6674080 | 0.83 | HPGD (1.00) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| SCHEMBL699230 | 0.83 | ALDH1A1 (0.71) | CYP1A2MAPK1LMNAALDH1A1HPGD | |
| Oxybenzone SCHEMBL5161586 | 0.83 | HPGD (1.00) | CYP1A2MAPK1LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | claimed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | claimed |
| CN-101346359-A | 5, 5' position connecting 1, 1'-biphenyl shaft chiral ligand and its synthesizing method | UNIV SHANGHAI JIAOTONG (CN) | 2009-01-14 | — | — | CN | claimed |
| CN-103517899-A | Chromene compounds | TOKUYAMA CORPROATION | 2014-01-15 | — | — | CN | disclosed |
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | disclosed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | disclosed |
| CN-101346359-A | 5, 5' position connecting 1, 1'-biphenyl shaft chiral ligand and its synthesizing method | UNIV SHANGHAI JIAOTONG (CN) | 2009-01-14 | — | — | CN | disclosed |
| CN-100348597-C | Process for synthesizing 5,5' bit connected 1,1'-diphenyl kind axle chirality ligand | UNIV SHANGHAI JIAOTONG (CN) | 2007-11-14 | — | — | CN | disclosed |
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | AHR, CXCR5, CYP1B1 | CYP1A2 36/4885MAPK1 2660/4885LMNA 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.