SCHEMBL29454191

SCHEMBL29454191

Cc1cc(N)c(Cl)c(Nc2ncc(Cl)cc2C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.33
RAB9A P51151 3/20 0.33
GAA P10253 3/20 0.33
MAPT P10636 3/20 0.33
NPC1 O15118 2/20 0.33
LMNA P02545 5/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
KDM4E B2RXH2 2/20 0.33
RAPGEF4 Q8WZA2 2/20 0.32
PIK3CA P42336 4/20 0.32
CRHR1 P34998 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232537 1.00 KMT2A (0.35) KMT2AHTTMEN1HSD17B10SMN1; SMN2
SCHEMBL31723256 1.00 KMT2A (0.35) KMT2AHTTMEN1HSD17B10SMN1; SMN2
SCHEMBL31723212 0.78 RAB9A (0.43) KMT2AMEN1SMN1; SMN2RAB9AGAA
SCHEMBL22232392 0.78 RAB9A (0.43) KMT2AMEN1SMN1; SMN2RAB9AGAA
SCHEMBL29454077 0.78 RAB9A (0.43) KMT2AMEN1SMN1; SMN2RAB9AGAA
SCHEMBL22232146 0.72 PLAU (0.37) KMT2AHTTMEN1SMN1; SMN2RAB9A
SCHEMBL29454055 0.72 PLAU (0.37) KMT2AHTTMEN1SMN1; SMN2RAB9A
SCHEMBL22231877 0.71 RAPGEF4 (0.58) GAAMAPTLMNAALDH1A1KDM4E
SCHEMBL31723199 0.71 RAPGEF4 (0.58) GAAMAPTLMNAALDH1A1KDM4E
SCHEMBL29454179 0.71 RAPGEF4 (0.58) GAAMAPTLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS KMT2A 438/4885HTT 1711/4885MEN1 1657/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS KMT2A 3264/4885HTT 4153/4885MEN1 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.