Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455275 | 0.91 | CASP1 (0.41) | CASP1HPGDKIF11SIRT2CHRM1 | |
| SCHEMBL30787947 | 0.89 | SMN1; SMN2 (0.40) | CASP1KIF11SIRT2SMN1; SMN2CHRM1 | |
| SCHEMBL29455257 | 0.80 | L3MBTL1 (0.36) | CASP1HPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL29455255 | 0.77 | L3MBTL1 (0.37) | CASP1HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL11885305 | 0.75 | KIF11 (0.45) | HPGDKIF11SIRT2MEN1RAB9A | |
| SCHEMBL29455260 | 0.74 | CYP3A4 (0.47) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1706149 | 0.73 | SIRT2 (0.47) | HPGDKIF11SIRT2RAB9A | |
| SCHEMBL6035963 | 0.73 | KMT2A (0.55) | KMT2A | |
| SCHEMBL3158110 | 0.73 | HDAC3 (0.46) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22468869 | 0.73 | KIF11 (0.57) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127797-A1 | PRODRUG COMPRISING A DRUG-LINKER CONJUGATE | ASCENDIS PHARMA A/S (DK) | 2025-04-24 | — | — | US | disclosed |
| US-20240041897-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA GMBH (DE) | 2024-02-08 | — | — | US | disclosed |
| US-20220331334-A1 | Prodrug Comprising a Drug-Linker Conjugate | ASCENDIS PHARMA A/S (DK) | 2022-10-20 | — | — | US | disclosed |
| EP-3981761-A2 | INTERMEDIATES FOR PRODRUGS | Ascendis Pharma A/S (DK) | 2022-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240041897-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | H1-0, H1-3, H1-2 | CASP1 1857/4885HPGD 1998/4885HDAC3 445/4885 |
| US-20220331334-A1 | Prodrug Comprising a Drug-Linker Conjugate | H1-0, H1-3, DLST | CASP1 2161/4885HPGD 1728/4885HDAC3 579/4885 |
| US-20250127797-A1 | PRODRUG COMPRISING A DRUG-LINKER CONJUGATE | H1-0, H1-3, DLST | CASP1 2161/4885HPGD 1728/4885HDAC3 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.