SCHEMBL29456038

SCHEMBL29456038

C=C1C(=O)O[C@H]2C[C@@H](C)[C@@H]3[C@@H](O)C[C@@H](O)[C@@]3(C)C[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 2/20 0.65
▸ MAPT P10636 4/20 0.50
▸ RAB9A P51151 4/20 0.50
▸ NPC1 O15118 3/20 0.50
▸ XBP1 P17861 3/20 0.50
▸ HTT P42858 3/20 0.50
▸ MDM2 Q00987 3/20 0.50
▸ PKM P14618 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ TERT O14746 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ GLA P06280 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ AGTR1 P30556 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ GPR55 Q9Y2T6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28044817 0.81 PTGS2 (0.59) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL31626700 0.81 PTGS2 (0.59) PTGS2MAPTRAB9ANPC1XBP1
Pseudoguaianolide SCHEMBL31387995 0.80 PTGS2 (0.55) PTGS2MAPTRAB9ANPC1XBP1
Burrodin SCHEMBL30072218 0.79 PTGS2 (1.00) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL26240701 0.79 PTGS2 (0.49) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL6424628 0.75 PTGS2 (0.53) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL30047291 0.69 PTGS2 (0.47) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL16641594 0.69 NPC1 (0.60) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL23106991 0.68 MAPT (0.49) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL31237447 0.68 PTGS2 (0.57) PTGS2MAPTRAB9ANPC1XBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243476-A1 PLANT LECTINS AS CARRIERS OF ASSOCIATED DRUG SUBSTANCES INTO ANIMAL AND HUMAN CELLS Biostrategies LC 2025-07-31 — — US claimed
US-20250002565-A1 HIV-BINDING PEPTIDES AND MEDICAL USE THEREOF COTROPIA JOSEPH (US) 2025-01-02 — — US claimed
WO-2024178091-A1 MATERIALS AND METHODS FOR THERAPY OF THE MUSCULOSKELETAL SYSTEM AND OTHER TISSUES Biostrategies LC (US) 2024-08-29 — — WO claimed
US-20240277802-A1 Materials and Methods for Therapy of the Musculoskeletal System and Other Tissues Biostrategies LC 2024-08-22 — — US claimed
EP-4402167-A1 HIV-BINDING PEPTIDES AND MEDICAL USE THEREOF Cotropia, Joseph (US) 2024-07-24 — — EP claimed
US-20230140157-A1 PLANT LECTINS AS CARRIERS OF ASSOCIATED DRUG SUBSTANCES INTO ANIMAL AND HUMAN CELLS Biostrategies LC 2023-05-04 — — US claimed
WO-2023043880-A1 HIV-BINDING PEPTIDES AND MEDICAL USE THEREOF COTROPIA JOSEPH (US) 2023-03-23 — — WO claimed
EP-3915587-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2026-03-25 — — EP disclosed
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2026-01-01 — — US disclosed
EP-4647436-A2 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES Sapreme Technologies B.V. (NL) 2025-11-12 — — EP disclosed
US-12453782-B2 Antibody-oligonucleotide conjugate SAPREME TECHNOLOGIES B.V. (NL) 2025-10-28 — — US disclosed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 — — EP disclosed
US-20250302983-A1 Saponin Conjugates SAPREME TECHNOLOGIES B.V. (NL) 2025-10-02 — — US disclosed
US-20220218837-A1 DRUG CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-07-14 — — US disclosed
US-11377649-B2 Plant lectins as carriers of associated drug substances into animal and human cells Biostrategies LC (US) 2022-07-05 — — US disclosed
EP-4015003-A1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-06-22 — — EP disclosed
WO-2022103263-A1 RODENTICIDE METAMETA RESEARCH B.V. (NL) 2022-05-19 — — WO disclosed
US-20220152213-A1 SHIGA TOXIN A SUBUNIT EFFECTOR POLYPEPTIDES, SHIGA TOXIN EFFECTOR SCAFFOLDS, AND CELL-TARGETING MOLECULES FOR SITE-SPECIFIC CONJUGATION ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE 2022-05-19 — — US disclosed
US-11312751-B2 MHC class I epitope delivering polypeptides MOLECULAR TEMPLATES, INC. (US) 2022-04-26 — — US disclosed
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302983-A1 Saponin Conjugates EPCAM, CD47, SHBG PTGS2 1886/4885MAPT 4204/4885RAB9A 3979/4885
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, FCGR3B PTGS2 3910/4885MAPT 3753/4885RAB9A 2151/4885
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, EGFR PTGS2 3604/4885MAPT 3868/4885RAB9A 3465/4885
US-20220218837-A1 DRUG CONJUGATE OSTC, ADCY7, ADCY3 PTGS2 2683/4885MAPT 4047/4885RAB9A 3950/4885
US-12453782-B2 Antibody-oligonucleotide conjugate CD40, FCGR1A, TNFSF10 PTGS2 3395/4885MAPT 4452/4885RAB9A 4519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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