Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358943 | 0.87 | HRH3 (0.48) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30205032 | 0.86 | ADRA2C (0.49) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28626345 | 0.85 | MEN1 (0.50) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13811408 | 0.84 | TP53 (0.56) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7288882 | 0.84 | ADRA2C (0.69) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7290259 | 0.78 | KDM4E (0.59) | SMN1; SMN2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9325465 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6570752 | 0.76 | NPC1 (0.58) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18457436 | 0.76 | MEN1 (0.55) | SMN1; SMN2MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14174974 | 0.75 | LMNA (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867776-A | Coated aramid pulp for rubber reinforcement | 巴斯夫欧洲公司 | 2022-08-05 | — | — | CN | disclosed |
| US-10759780-B2 | Hindered amines | 3V SIGMA S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2020-07-30 | — | — | US | disclosed |
| EP-3424977-B1 | HINDERED POLYMERIC AMINES | 3V SIGMA SPA (IT) | 2020-03-18 | — | — | EP | disclosed |
| EP-3428156-B1 | HINDERED AMINES | 3V SIGMA SPA (IT) | 2020-02-12 | — | — | EP | disclosed |
| US-20190016702-A1 | HINDERED AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-17 | — | — | US | disclosed |
| EP-3428156-A1 | HINDERED AMINES | 3V SIGMA S.p.A (IT) | 2019-01-16 | — | — | EP | disclosed |
| EP-3424977-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.p.A (IT) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002631-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-03 | — | — | US | disclosed |
| US-9725578-B2 | Sterically hindered polymeric amines and their use as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2017-08-08 | — | — | US | disclosed |
| EP-2366732-B1 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA SPA (IT) | 2013-06-26 | — | — | EP | disclosed |
| US-8404765-B2 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2013-03-26 | — | — | US | disclosed |
| WO-2012153260-A1 | MIXTURE OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION | 3V SIGMA S.P.A. (IT) | 2012-11-15 | — | — | WO | disclosed |
| EP-2216364-B9 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA SPA (IT) | 2012-08-15 | — | — | EP | disclosed |
| WO-2012055965-A1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2012-05-03 | — | — | WO | disclosed |
| EP-2216364-B1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA SPA (IT) | 2012-03-14 | — | — | EP | disclosed |
| EP-2366732-A2 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA S.p.A (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224336-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION | 3V SIGMA S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2010-08-12 | — | — | US | disclosed |
| EP-2216364-A1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | PARG, PARN, PUF60 | SMN1; SMN2 3625/4885MEN1 3004/4885CYP3A4 2960/4885 |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | CBR3, SIGMAR1, NPSR1 | SMN1; SMN2 2800/4885MEN1 3952/4885CYP3A4 2425/4885 |
| US-20190016702-A1 | HINDERED AMINES | PARG, TAAR5, PARN | SMN1; SMN2 4076/4885MEN1 2944/4885CYP3A4 2383/4885 |
| US-10759780-B2 | Hindered amines | PARG, TAAR5, PARN | SMN1; SMN2 4076/4885MEN1 2944/4885CYP3A4 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.