SCHEMBL29459607

SCHEMBL29459607

Nc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.67
KDM4E B2RXH2 3/20 0.67
NPC1 O15118 3/20 0.67
ALDH1A1 P00352 2/20 0.67
MAPT P10636 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
JAK2 O60674 2/20 0.58
TYK2 P29597 2/20 0.58
PPARG P37231 1/20 0.58
PPARA Q07869 1/20 0.58
SMN1; SMN2 Q16637 3/20 0.57
NPSR1 Q6W5P4 2/20 0.57
HSD17B10 Q99714 1/20 0.57
PYGL P06737 2/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
JAK1 P23458 1/20 0.54
GFER P55789 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11219138 1.00 RAB9A (0.67) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL25395048 0.94 MAPT (0.66) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL28582515 0.88 ALDH1A1 (0.67) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL14228181 0.86 RAB9A (0.64) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL11576194 0.85 RAB9A (0.59) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL16592505 0.85 PYGL (0.67) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL29617476 0.85 KCNMA1 (0.68) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL11887644 0.85 KCNMA1 (0.68) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL11574839 0.83 NPC1 (0.61) RAB9AKDM4ENPC1ALDH1A1MAPT
SCHEMBL678770 0.83 JAK2 (0.68) RAB9AKDM4ENPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12139717-B2 Improving plant regeneration KWS SAAT SE & Co. KGaA (DE) 2024-11-12 US claimed
CN-118909909-A Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-11-08 CN claimed
CN-113544256-B Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-08-13 CN claimed
US-20220056461-A1 IMPROVING PLANT REGENERATION KWS SAAT SE & Co. KGaA (DE) 2022-02-24 US claimed
US-12139717-B2 Improving plant regeneration KWS SAAT SE & Co. KGaA (DE) 2024-11-12 US disclosed
US-12139717-B2 Improving plant regeneration KWS SAAT SE & Co. KGaA (DE) 2024-11-12 US disclosed
CN-118909909-A Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-11-08 CN disclosed
CN-118909909-A Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-11-08 CN disclosed
CN-113544256-B Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-08-13 CN disclosed
CN-113544256-B Improving plant regeneration 科沃施种子欧洲股份两合公司 2024-08-13 CN disclosed
US-20220056461-A1 IMPROVING PLANT REGENERATION KWS SAAT SE & Co. KGaA (DE) 2022-02-24 US disclosed
US-20220056461-A1 IMPROVING PLANT REGENERATION KWS SAAT SE & Co. KGaA (DE) 2022-02-24 US disclosed