SCHEMBL29461365

SCHEMBL29461365

CC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)CNC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CO)C(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KLK5 Q9Y337 2/20 0.57
NPY2R P49146 5/20 0.56
PRLHR P49683 3/20 0.56
RXFP4 Q8TDU9 5/20 0.55
RXFP3 Q9NSD7 5/20 0.55
F11 P03951 1/20 0.54
CXCR4 P61073 2/20 0.53
GLP1R P43220 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152284 0.88 PRLHR (0.63) NPY2RPRLHRGLP1R
SCHEMBL20003753 0.78 PRLHR (0.58) NPY2RPRLHRRXFP4RXFP3GLP1R
SCHEMBL31277132 0.77 KRAS (0.57) NPY2RPRLHRCXCR4
SCHEMBL29365385 0.76 KLKB1 (0.61)
SCHEMBL23056722 0.75 TEAD1 (0.53) NPY2RPRLHRRXFP4RXFP3CXCR4
SCHEMBL27014090 0.75 TEAD1 (0.53) NPY2RPRLHRRXFP4RXFP3CXCR4
SCHEMBL20402542 0.75 MC4R (0.53) NPY2RRXFP4RXFP3CXCR4GLP1R
SCHEMBL20003972 0.75 MC4R (0.53) NPY2RRXFP4RXFP3CXCR4GLP1R
SCHEMBL29482473 0.74 F11 (0.56) PRLHRF11GLP1R
SCHEMBL30883974 0.74 KLK5 (0.55) KLK5RXFP4RXFP3F11GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116870204-A Self-limiting Auger electron medicine of coronavirus and preparation method and application thereof 上海珺纳医疗科技有限公司 2023-10-13 CN claimed
US-20230184786-A1 Methods of Detecting and Treating Immune Responses Associated with Viral Infection FORSYTH DENTAL INFIRMARY FOR CHILDREN, d/b/a THE FORSYTH INSTITUTE 2023-06-15 US claimed
WO-2023094571-A1 STABILIZATION OF ACE2 FUSION PROTEINS FORMYCON AG (DE) 2023-06-01 WO claimed
US-20230149361-A1 METHODS OF TREATING CORONAVIRUS INFECTIONS USING ANGIOTENSIN-CONVERTING ENZYME 2 INHIBITORS Kumuda Inc. (US) 2023-05-18 US claimed
US-20230111350-A1 Opthalmic Compositions for Treating Coronaviruses ZEBRA BIOTECH PTY LTD (AU) 2023-04-13 US claimed
CN-112043838-B ACE2 receptor targeted nuclide polypeptide probe, and preparation method and application thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-07-26 CN claimed
EP-4702027-A1 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINE C-NUCLEOSIDE COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. (US) 2026-03-04 EP disclosed
US-20260053741-A1 HYDROGEL COMPRISING GLYCEROL AND A CARBOMER FOR TREATING THE RESPIRATORY SYMPTOMS OF COVID-19 DISEASE VIA THE NASAL ROUTE COSMOSOFT (FR) 2026-02-26 US disclosed
US-20260000618-A1 PHARMACEUTICAL FORMULATIONS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-01-01 US disclosed
US-12448383-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2025-10-21 US disclosed
US-20250296936-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2025-09-25 US disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-20250276979-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2025-09-04 US disclosed
WO-2022167526-A1 METHOD FOR PROGNOSING THE COURSE OF A SARS-COV-2 INFECTION AND THE RESPONSE TO A SARS-COV-2 IMMUNIZATION AND/OR NATURAL INFECTION BY MEASURING SOLUBLE ACE2 MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (DE) 2022-08-11 WO disclosed
EP-4039818-A1 METHOD FOR PROGNOSING THE COURSE OF A SARS-COV-2 INFECTION AND THE RESPONSE TO A SARS-COV-2 IMMUNIZATION AND/OR NATURAL INFECTION BY MEASURING SOLUBLE ACE2 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) 2022-08-10 EP disclosed
CN-112043838-B ACE2 receptor targeted nuclide polypeptide probe, and preparation method and application thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-07-26 CN disclosed
CN-112043838-B ACE2 receptor targeted nuclide polypeptide probe, and preparation method and application thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-07-26 CN disclosed
CN-112403309-B High-precision proportioning material proportioning device for electroceramic processing 江西铂川自动化科技有限公司 2022-07-22 CN disclosed
EP-3973794-A1 FRAGRANCE-CONTAINING SHEET FOR HEATING-TYPE FLAVOR INHALER, AND HEATING-TYPE FLAVOR INHALER Japan Tobacco Inc. (JP) 2022-03-30 EP disclosed
WO-2022053993-A2 TREATMENTS FOR SARS-COV-2 INFECTION (COVID-19) MYLAN LABORATORIES LIMITED (IN) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000618-A1 PHARMACEUTICAL FORMULATIONS AND USES THEREOF PRNP, F7, F5 KLK5 753/4885NPY2R 2912/4885PRLHR 3314/4885
US-20230149361-A1 METHODS OF TREATING CORONAVIRUS INFECTIONS USING ANGIOTENSIN-CONVERTING ENZYME 2 INHIBITORS ACE2, ACE, AGT KLK5 175/4885NPY2R 605/4885PRLHR 1618/4885
US-20250276979-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE KLK5 428/4885NPY2R 3175/4885PRLHR 3810/4885
US-12448383-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, OAT KLK5 1937/4885NPY2R 4579/4885PRLHR 4555/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE KLK5 428/4885NPY2R 3175/4885PRLHR 3810/4885
US-20250296936-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE KLK5 432/4885NPY2R 3130/4885PRLHR 3804/4885
US-20260053741-A1 HYDROGEL COMPRISING GLYCEROL AND A CARBOMER FOR TREATING THE RESPIRATORY SYMPTOMS OF COVID-19 DISEASE VIA THE NASAL ROUTE ACE2, FURIN, PRSS2 KLK5 1187/4885NPY2R 877/4885PRLHR 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.