SCHEMBL29462949

SCHEMBL29462949

CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 8/20 0.64
▸ TLR2 O60603 2/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ MDM4 O15151 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ CASP3 P42574 1/20 0.49
▸ GRB2 P62993 1/20 0.49
▸ MDM2 Q00987 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30386840 1.00 PTPN1 (0.64) PTPN1TLR2KMT2AMDM4TP53
SCHEMBL29872083 0.92 PTPN1 (0.60) PTPN1TLR2MDM4TP53GRB2
SCHEMBL30153671 0.92 PTPN1 (0.56) PTPN1MDM4TP53CASP3MDM2
SCHEMBL29700028 0.92 PTPN1 (0.56) PTPN1MDM4TP53CASP3MDM2
SCHEMBL29990051 0.92 PTPN1 (0.56) PTPN1MDM4TP53CASP3MDM2
SCHEMBL12658035 0.92 PTPN1 (0.58) PTPN1TLR2KMT2AMDM4TP53
SCHEMBL30163429 0.91 PTPN1 (0.56) PTPN1TLR2KMT2ACASP3GRB2
SCHEMBL29505149 0.90 CASP3 (0.56) PTPN1KMT2AMDM4TP53CASP3
SCHEMBL14719947 0.90 KMT2A (0.57) PTPN1TLR2KMT2AMDM4TP53
SCHEMBL14997839 0.89 KMT2A (0.58) PTPN1TLR2KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933634-B Synthesis method of acetyl hexadecapeptide 陕西未来多肽生物科技有限公司 2024-08-09 — — CN claimed
CN-113501871-B Method for preparing darunavagon by combining solid phase with liquid phase 汉肽生物医药集团有限公司 2022-10-28 — — CN claimed
CN-114933634-A Synthesis method of acetyl hexapeptide 陕西未来多肽生物科技有限公司 2022-08-23 — — CN claimed
CN-113880936-B Solid-phase synthesis method of abamectin 浙江湃肽生物有限公司南京分公司 2022-03-29 — — CN claimed
CN-118955683-A Semex lattice Synthesis method of lupeptide 泰州兴普泰生物制药有限公司 2024-11-15 — — CN disclosed
US-20240319146-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS PEPTISTAR INC. (JP) 2024-09-26 — — US disclosed
CN-114933634-B Synthesis method of acetyl hexadecapeptide 陕西未来多肽生物科技有限公司 2024-08-09 — — CN disclosed
EP-4365184-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS Peptistar Inc. (JP) 2024-05-08 — — EP disclosed
WO-2023277186-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS ペプチスター株式会社 2023-01-05 — — WO disclosed
CN-113501871-B Method for preparing darunavagon by combining solid phase with liquid phase 汉肽生物医药集团有限公司 2022-10-28 — — CN disclosed
CN-113501871-B Method for preparing darunavagon by combining solid phase with liquid phase 汉肽生物医药集团有限公司 2022-10-28 — — CN disclosed
CN-114933634-A Synthesis method of acetyl hexapeptide 陕西未来多肽生物科技有限公司 2022-08-23 — — CN disclosed
CN-111349155-B Glucagon analogue and preparation method and application thereof 浙江和泽医药科技股份有限公司 2022-04-05 — — CN disclosed
CN-113880936-B Solid-phase synthesis method of abamectin 浙江湃肽生物有限公司南京分公司 2022-03-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240319146-A1 ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS HDGF, VIP, NPPA PTPN1 4090/4885TLR2 4291/4885KMT2A 4517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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