Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 7/20 | 0.33 |
| ▸ | PRKCA | P17252 | 4/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19968854 | 1.00 | KIF18A (0.33) | KIF18APRKCAPRKCQMEN1KMT2A | |
| SCHEMBL19925244 | 0.92 | SCN9A (0.33) | KIF18AMEN1KMT2ASCN9AOPRM1 | |
| SCHEMBL29464451 | 0.92 | SCN9A (0.33) | KIF18AMEN1KMT2ASCN9AOPRM1 | |
| SCHEMBL19925274 | 0.90 | RORC (0.36) | KIF18APRKCAPRKCQSCN9APTPN11 | |
| SCHEMBL29464942 | 0.90 | RORC (0.36) | KIF18APRKCAPRKCQSCN9APTPN11 | |
| SCHEMBL19925765 | 0.88 | WDR5 (0.33) | KIF18ASCN9AOPRM1PTPN11 | |
| SCHEMBL29464958 | 0.88 | SMO (0.33) | KIF18AOPRM1PTPN11GAA | |
| SCHEMBL19927758 | 0.88 | SMO (0.33) | KIF18AOPRM1PTPN11GAA | |
| SCHEMBL29464865 | 0.88 | JAK2 (0.33) | KIF18ASCN9A | |
| SCHEMBL19925121 | 0.88 | JAK2 (0.33) | KIF18ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |