Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 5/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925244 | 1.00 | SCN9A (0.33) | SCN9AJAK2JAK1JAK3TACR1 | |
| SCHEMBL29464906 | 0.92 | KIF18A (0.33) | SCN9AOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL19968854 | 0.92 | KIF18A (0.33) | SCN9AOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL19925765 | 0.91 | WDR5 (0.33) | SCN9AJAK2JAK1JAK3OPRM1 | |
| SCHEMBL29464865 | 0.91 | JAK2 (0.33) | SCN9AJAK2JAK1JAK3KIF18A | |
| SCHEMBL19925121 | 0.91 | JAK2 (0.33) | SCN9AJAK2JAK1JAK3KIF18A | |
| SCHEMBL19925001 | 0.90 | RORC (0.35) | SCN9ATACR1KIF18ASCN1ASCN8A | |
| SCHEMBL29464323 | 0.90 | RORC (0.35) | SCN9ATACR1KIF18ASCN1ASCN8A | |
| SCHEMBL19925158 | 0.89 | ALDH1A1 (0.33) | JAK2JAK1JAK3OPRM1OPRD1 | |
| SCHEMBL19951309 | 0.87 | RBP4 (0.34) | SCN9AKIF18ASCN1ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |