Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Propyromazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 16/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propyromazine SCHEMBL26291 | 1.00 | BCHE (0.55) | BCHEHTR2AHTR1AADRB3HTR2C | |
| SCHEMBL11618902 | 0.73 | BCHE (0.67) | BCHEHTR2AHTR1AADRB3HTR2C | |
| SCHEMBL4443462 | 0.70 | BCHE (0.63) | BCHEHTR2AHTR1AADRB3HTR2C | |
| SCHEMBL11315494 | 0.69 | BCHE (1.00) | BCHEACHENOX1MAPT | |
| SCHEMBL1320997 | 0.69 | BCHE (1.00) | BCHEHTR2AHTR1AADRB3HTR2C | |
| SCHEMBL29548285 | 0.69 | BCHE (1.00) | BCHEHTR2AHTR1AADRB3HTR2C | |
| Hydrochloric Acid SCHEMBL159034 | 0.68 | ACHE (1.00) | BCHEHTR2AHTR1AADRB3HTR2C | |
| Hydrochloric Acid SCHEMBL30259425 | 0.68 | ACHE (1.00) | BCHEHTR2AHTR1AADRB3HTR2C | |
| SCHEMBL341905 | 0.67 | NOX1 (1.00) | BCHEACHENOX1POLBATM | |
| SCHEMBL30198410 | 0.67 | NOX1 (1.00) | BCHEACHENOX1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216447178-U | Backward centrifugal fan | 广东顺威精密塑料股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| EP-4218976-B1 | CONTROL SYSTEM, INFORMATION SYSTEM, INFORMATION PROCESSING METHOD, AND PROGRAM | KONAMI DIGITAL ENTERTAINMENT CO LTD (JP) | 2026-04-22 | — | — | EP | disclosed |
| US-12552818-B2 | Polycyclic compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2026-02-17 | — | — | US | disclosed |
| US-12508506-B2 | Control system, information system, information processing method, and computer-readable recording medium | KONAMI DIGITAL ENTERTAINMENT CO., LTD. (JP) | 2025-12-30 | — | — | US | disclosed |
| CN-116582391-B | Multi-ECU data polling transmission method for commercial vehicle | 东风商用车有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20240406421-A1 | IMAGE DECODING APPARATUS | HUAWEI TECH CO LTD (CN) | 2024-12-05 | — | — | US | disclosed |
| EP-3782548-B1 | PROGRAM, INFORMATION PROCESSING DEVICE, AND INFORMATION PROCESSING METHOD | SONY GROUP CORP (JP) | 2024-12-04 | — | — | EP | disclosed |
| US-12034948-B2 | Image decoding apparatus | HUAWEI TECHNOLOGIES CO., LTD. (CN) | 2024-07-09 | — | — | US | disclosed |
| CN-117759295-A | Vertical double-liner coal bunker and safety construction method thereof | 新汶矿业集团有限责任公司华丰煤矿 | 2024-03-26 | — | — | CN | disclosed |
| CN-117666829-A | Sensor device and display device | 三星显示有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20230104248-A1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-04-06 | — | — | US | disclosed |
| US-20220286693-A1 | IMAGE DECODING APPARATUS | HUAWEI TECHNOLOGIES CO., LTD. (CN) | 2022-09-08 | — | — | US | disclosed |
| WO-2022153993-A1 | GAME SYSTEM, GAME CONTROL METHOD, AND PROGRAM | 株式会社コナミアミューズメント | 2022-07-21 | — | — | WO | disclosed |
| WO-2022138203-A1 | CONTROL SYSTEM, INFORMATION SYSTEM, INFORMATION PROCESSING METHOD, AND PROGRAM | 株式会社コナミデジタルエンタテインメント | 2022-06-30 | — | — | WO | disclosed |
| US-11356682-B2 | Image decoding apparatus | HUAWEI TECHNOLOGIES CO., LTD. (CN) | 2022-06-07 | — | — | US | disclosed |
| CN-114450917-A | High-safety network communication method and system | 量子特性技术有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-216447178-U | Backward centrifugal fan | 广东顺威精密塑料股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-20220125903-A1 | METHODS FOR IMPROVING THE EFFICACY OF A SURVIVIN THERAPEUTIC IN THE TREATMENT OF TUMORS | IMMUNOVACCINE TECHNOLOGIES INC. (CA) | 2022-04-28 | — | — | US | disclosed |
| CN-108614877-B | Method and system for monitoring data replication process based on token bucket | 携程商旅信息服务（上海）有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20220077433-A1 | Manufacturing method for light emitting device, light emitting device, and hybrid light emitting device | NAJING TECH CORP LTD (CN) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552818-B2 | Polycyclic compounds for organic electroluminescent devices | SCO2, ESRRA, LBR | ACHE 4759/4885BCHE 4371/4885HTR2A 1892/4885 |
| US-20230104248-A1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | VDAC2, VDAC3, KCNC1 | ACHE 1146/4885BCHE 2245/4885HTR2A 3722/4885 |
| US-12508506-B2 | Control system, information system, information processing method, and computer-readable recording medium | SET, TMCO1, GZMB | ACHE 648/4885BCHE 1944/4885HTR2A 1145/4885 |
| US-20220125903-A1 | METHODS FOR IMPROVING THE EFFICACY OF A SURVIVIN THERAPEUTIC IN THE TREATMENT OF TUMORS | BIRC5, XIAP, BIRC2 | ACHE 4834/4885BCHE 3991/4885HTR2A 4262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.