Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 9/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946551 | 0.90 | CDK1 (0.41) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL2951209 | 0.88 | KDM4E (0.42) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL2951937 | 0.85 | DHFR (0.45) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL3040612 | 0.75 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL30399128 | 0.75 | FYN (0.41) | DHFRHRH4 | |
| SCHEMBL2946049 | 0.73 | DHFR (0.42) | CDK1CDK2CCNB1CCNE1DHFR | |
| SCHEMBL2950165 | 0.73 | TLR7 (0.41) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL2954051 | 0.72 | DHFR (0.44) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL2952950 | 0.72 | DHFR (0.43) | DHFR | |
| SCHEMBL22411506 | 0.71 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |