Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.33 |
| ▸ | CHRNG | P07510 | 4/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | CHRND | Q07001 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946675 | 1.00 | SLC6A3 (0.36) | SLC6A3ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL43590 | 0.85 | SLC6A3 (0.44) | SLC6A3ALDH1A1MAPTMMEACE | |
| SCHEMBL43589 | 0.85 | SLC6A3 (0.44) | SLC6A3ALDH1A1MAPTMMEACE | |
| SCHEMBL289160 | 0.85 | SLC6A3 (0.44) | SLC6A3ALDH1A1MAPTMMEACE | |
| SCHEMBL1716976 | 0.85 | SLC6A3 (0.44) | SLC6A3ALDH1A1MAPTMMEACE | |
| Hydrochloric Acid SCHEMBL8190787 | 0.83 | SLC6A3 (0.42) | SLC6A3ALDH1A1MAPTMMEACE | |
| Hydrochloric Acid SCHEMBL8190786 | 0.83 | SLC6A3 (0.42) | SLC6A3ALDH1A1MAPTMMEACE | |
| Hydrochloric Acid SCHEMBL29399049 | 0.83 | SLC6A3 (0.42) | SLC6A3ALDH1A1MAPTMMEACE | |
| SCHEMBL41886 | 0.80 | — | — | |
| SCHEMBL1717828 | 0.80 | HMGCR (0.41) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080785-B2 | Albumin fusion proteins | NOVOZYMES BIOPHARMA DK A/S (DK) | 2018-09-25 | — | — | US | disclosed |
| US-7785599-B2 | Using interferon alpha chimera to treat and prevent cell proliferative and viral diseases | HUMAN GENOME SCIENCES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20090285816-A9 | Albumin Fusion Proteins | HUMAN GENOME SCIENCES, INC. | 2009-11-19 | — | — | US | disclosed |
| US-20090105140-A1 | Albumin Fusion Proteins | HUMAN GENOME SCIENCES, INC. | 2009-04-23 | — | — | US | disclosed |
| US-20080267962-A1 | Immunoglobulin fusion for treatment and prevention of cell proliferative and blood disorders | HUMAN GENOME SCIENCES, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269127-A1 | Protein C; kits; pharmacokinetics | HUMAN GENOME SCIENCES, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269128-A1 | Apolipoproteins; kits; pharmacokinetics | HUMAN GENOME SCIENCES, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269125-A1 | Factor IX polypeptide fusion for treatment and prevention of cell proliferative, inflammatory, respiratory system and blood disorders; enhancing half-live of serum polypeptides | HUMAN GENOME SCIENCES, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269126-A1 | Factor X polypeptide fusion for treatment and prevention of cell proliferative, inflammatory, respiratory system and blood disorders; prolonging half-lives of serum polypeptides | HUMAN GENOME SCIENCES, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080261877-A1 | Antihemophilic factor; kits; pharmacokinetics | HUMAN GENOME SCIENCES, INC. | 2008-10-23 | — | — | US | disclosed |
| US-20080131399-A1 | Using interferon alpha chimera to treat and prevent cell proliferative and viral diseases | HUMAN GENOME SCIENCES, INC. | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267962-A1 | Immunoglobulin fusion for treatment and prevention of cell proliferative and blood disorders | ALB, HDGF, HAVCR2 | SLC6A3 2791/4885ALDH1A1 2744/4885LMNA 1599/4885 |
| US-20080269126-A1 | Factor X polypeptide fusion for treatment and prevention of cell proliferative, inflammatory, respiratory system and blood disorders; prolonging half-lives of serum polypeptides | F13B, F11, PGF | SLC6A3 4448/4885ALDH1A1 3658/4885LMNA 708/4885 |
| US-20090285816-A9 | Albumin Fusion Proteins | ALB, FABP1, TTR | SLC6A3 3290/4885ALDH1A1 2567/4885LMNA 1971/4885 |
| US-20090105140-A1 | Albumin Fusion Proteins | ALB, FABP1, HDGF | SLC6A3 3219/4885ALDH1A1 2350/4885LMNA 2158/4885 |
| US-20080131399-A1 | Using interferon alpha chimera to treat and prevent cell proliferative and viral diseases | HDGF, IRF3, ALB | SLC6A3 3715/4885ALDH1A1 1872/4885LMNA 1865/4885 |
| US-20080269127-A1 | Protein C; kits; pharmacokinetics | ALB, FABP1, FABP3 | SLC6A3 2722/4885ALDH1A1 3173/4885LMNA 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.