Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | AOC1 | P19801 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527773 | 0.87 | LOXL2 (0.48) | LOXL2AOC1AOC3PNMTHRH3 | |
| SCHEMBL5513336 | 0.82 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL961729 | 0.80 | PNMT (0.44) | LOXL2AOC1AOC3PNMTALDH1A1 | |
| SCHEMBL13743153 | 0.79 | AOC1 (0.33) | LOXL2AOC1AOC3ALDH1A1 | |
| SCHEMBL31432074 | 0.79 | CYP3A4 (0.42) | LOXL2AOC1AOC3PNMTALDH1A1 | |
| SCHEMBL27674631 | 0.79 | LOXL2 (0.34) | LOXL2AOC1AOC3PNMT | |
| SCHEMBL20149212 | 0.78 | FEN1 (0.37) | ALDH1A1 | |
| SCHEMBL20149118 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31431058 | 0.78 | CYP3A4 (0.41) | LOXL2AOC1AOC3PNMTALDH1A1 | |
| SCHEMBL5513611 | 0.78 | ALDH1A1 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206870-B | Tricyclic AKR1C 3-dependent KARS inhibitors | 诺华股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114206870-A | Tricyclic AKR1C3 dependent KARS inhibitors | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |