SCHEMBL29468849

SCHEMBL29468849

CC(C)(C)OC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 10/20 0.45
▸ GRB2 P62993 1/20 0.44
▸ NTSR2 O95665 3/20 0.41
▸ NTSR1 P30989 2/20 0.41
▸ F2 P00734 1/20 0.39
▸ SORT1 Q99523 1/20 0.38
▸ ACE P12821 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30937369 0.89 REN (0.43) RENGRB2NTSR2F2ACE
SCHEMBL29468784 0.88 REN (0.46) RENGRB2NTSR2NTSR1F2
SCHEMBL29658176 0.88 GRB2 (0.44) RENGRB2NTSR2NTSR1F2
SCHEMBL29468837 0.87 KMT2A (0.41) GRB2
SCHEMBL29962469 0.87 REN (0.44) RENNTSR2F2ACE
SCHEMBL30543482 0.87 GRB2 (0.52) RENGRB2NTSR2NTSR1F2
SCHEMBL30028210 0.87 REN (0.39) RENGRB2
SCHEMBL29669249 0.87 REN (0.45) RENGRB2NTSR2F2
SCHEMBL31399255 0.86 REN (0.44) RENGRB2NTSR2F2
SCHEMBL30972553 0.85 KMT2A (0.42) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 REN 2171/4885GRB2 524/4885NTSR2 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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