SCHEMBL29468784

SCHEMBL29468784

C[C@H](NC(=O)CNC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 10/20 0.46
▸ GRB2 P62993 1/20 0.42
▸ NTSR1 P30989 3/20 0.41
▸ NTSR2 O95665 1/20 0.41
▸ F2 P00734 1/20 0.38
▸ OPRM1 P35372 1/20 0.38
▸ OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30455472 0.93 GRB2 (0.39) RENGRB2OPRM1OPRD1
SCHEMBL29468867 0.93 GRB2 (0.39) RENGRB2OPRM1OPRD1
SCHEMBL30220497 0.90 REN (0.46) RENGRB2OPRM1OPRD1
SCHEMBL30543480 0.90 GRB2 (0.46) GRB2NTSR1NTSR2F2OPRM1
SCHEMBL29468832 0.89 GRB2 (0.46) GRB2NTSR1NTSR2F2OPRM1
SCHEMBL38651991 0.89 APLNR (0.43) GRB2NTSR1NTSR2F2OPRM1
SCHEMBL29468849 0.88 REN (0.45) RENGRB2NTSR1NTSR2F2
SCHEMBL30543476 0.88 GRB2 (0.44) GRB2NTSR1NTSR2F2OPRM1
SCHEMBL38651853 0.87 GRB2 (0.48) RENGRB2NTSR1NTSR2F2
SCHEMBL30543475 0.84 GRB2 (0.41) GRB2NTSR1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2023-08-03 — — US disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 REN 2171/4885GRB2 524/4885NTSR1 78/4885
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 REN 2171/4885GRB2 524/4885NTSR1 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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