Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333797 | 1.00 | GFER (0.37) | GFERFABP1KMT2ALDHAHCRTR1 | |
| SCHEMBL24333372 | 0.87 | DCTPP1 (0.37) | GFERFABP1KMT2ALDHAALDH1A1 | |
| SCHEMBL29469870 | 0.87 | DCTPP1 (0.37) | GFERFABP1KMT2ALDHAALDH1A1 | |
| SCHEMBL29469919 | 0.85 | CNR2 (0.37) | GFERFABP1KMT2ALDHAALDH1A1 | |
| SCHEMBL29469675 | 0.83 | MAPT (0.39) | KMT2AALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL24334259 | 0.83 | MAPT (0.39) | KMT2AALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL24334001 | 0.82 | POLB (0.42) | GFERFABP1KMT2ALDHAALDH1A1 | |
| SCHEMBL29469820 | 0.82 | POLB (0.42) | GFERFABP1KMT2ALDHAALDH1A1 | |
| SCHEMBL29469666 | 0.82 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPK1SLC40A1GAA | |
| SCHEMBL24334212 | 0.82 | CCKBR (0.42) | GFERPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |