Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | COMT | P21964 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333372 | 1.00 | DCTPP1 (0.37) | DCTPP1KMT2AMEN1TDP1RXFP1 | |
| SCHEMBL24333797 | 0.87 | GFER (0.37) | KMT2AALDH1A1NPC1RAB9ACOMT | |
| SCHEMBL29469855 | 0.87 | GFER (0.37) | KMT2AALDH1A1NPC1RAB9ACOMT | |
| SCHEMBL29469702 | 0.85 | DRD2 (0.35) | KMT2ARXFP1MAPTALDH1A1GFER | |
| SCHEMBL24334212 | 0.85 | CCKBR (0.42) | GFER | |
| SCHEMBL24333991 | 0.85 | KMT2A (0.33) | KMT2AMEN1TDP1RXFP1MAPT | |
| SCHEMBL29469818 | 0.85 | KMT2A (0.33) | KMT2AMEN1TDP1RXFP1MAPT | |
| SCHEMBL29469648 | 0.84 | KMT2A (0.36) | KMT2AMEN1TDP1RXFP1MAPT | |
| SCHEMBL24333957 | 0.84 | S1PR3 (0.33) | KMT2AMEN1TDP1RXFP1MAPT | |
| SCHEMBL29469656 | 0.84 | S1PR3 (0.33) | KMT2AMEN1TDP1RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |