Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26547708 | 0.84 | TNFRSF1A (0.44) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL26547632 | 0.81 | CYP19A1 (0.43) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL26547697 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL26547732 | 0.80 | ACACB (0.38) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL26547712 | 0.79 | HPGD (0.42) | MEN1KMT2AKDM4EHPGDADORA2B | |
| SCHEMBL31248637 | 0.76 | BRPF1 (0.43) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL26547693 | 0.75 | NPC1 (0.48) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31248639 | 0.75 | KMT2A (0.34) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL31248652 | 0.75 | MEN1 (0.34) | MEN1KMT2AL3MBTL1ALDH1A1HIF1A | |
| SCHEMBL31248757 | 0.75 | SMN1; SMN2 (0.37) | MEN1KMT2AL3MBTL1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4210683-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | Aurigene Oncology Limited (IN) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022053967-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-03-17 | — | — | WO | disclosed |