SCHEMBL31248652

SCHEMBL31248652

Cc1cc2c(Br)cc(OC(F)(F)Br)cc2n(C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ EGFR P00533 1/20 0.33
▸ BRPF1 P55201 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ IDO1 P14902 1/20 0.31
▸ PGR P06401 2/20 0.31
▸ NR1H3 Q13133 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ CYP19A1 P11511 1/20 0.30
▸ NQO2 P16083 1/20 0.30
▸ HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31248757 0.92 SMN1; SMN2 (0.37) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL26547632 0.84 CYP19A1 (0.43) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL31248756 0.83 MEN1 (0.34) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL31248639 0.81 KMT2A (0.34) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL26547726 0.81 KMT2A (0.34) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL31248637 0.79 BRPF1 (0.43) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL26547732 0.77 ACACB (0.38) MEN1KMT2AL3MBTL1EGFRBRPF1
SCHEMBL26547697 0.76 ALDH1A1 (0.36) MEN1KMT2AL3MBTL1EGFRLMNA
SCHEMBL31426258 0.76 BRPF1 (0.40) MEN1KMT2AL3MBTL1BRPF1LMNA
SCHEMBL26547742 0.76 BRPF1 (0.40) MEN1KMT2AL3MBTL1EGFRBRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
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