SCHEMBL31248639

SCHEMBL31248639

Cc1cc2c(Br)cc(OC(F)F)cc2n(C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ BRPF1 P55201 2/20 0.33
▸ EGFR P00533 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ PIK3CA P42336 1/20 0.32
▸ PRKDC P78527 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ BRD4 O60885 1/20 0.31
▸ JAK2 O60674 1/20 0.30
▸ BTK Q06187 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ CYP19A1 P11511 1/20 0.30
▸ NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26547726 1.00 KMT2A (0.34) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL31248637 0.87 BRPF1 (0.43) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL26547632 0.84 CYP19A1 (0.43) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL26547732 0.83 ACACB (0.38) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL31248652 0.81 MEN1 (0.34) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL31248757 0.81 SMN1; SMN2 (0.37) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL31248756 0.77 MEN1 (0.34) KMT2AMEN1L3MBTL1BRPF1EGFR
SCHEMBL26547697 0.76 ALDH1A1 (0.36) KMT2AMEN1L3MBTL1EGFRLMNA
SCHEMBL31426258 0.76 BRPF1 (0.40) KMT2AMEN1L3MBTL1BRPF1LMNA
SCHEMBL26547742 0.76 BRPF1 (0.40) KMT2AMEN1L3MBTL1BRPF1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
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